Antidepressants and Receptor Function

Symposium on Depression, antidepressants and receptor sensitivity, held at the Ciba Foundation, London, 19–21 November 1985

Editors: Ruth Porter, Gregory Bock (Organizer) and Sarah Clark

D. Murphy Introduction

S.Z. Langer, A.M. Galzin, C.R. Lee and H. Schoemaker Antidepressant-binding sites in brain and platelets

Discussion

W.H. Berrettini, J. Bardakjian, A.L. Barnett Jr, J.I. Nurnberger Jr and E.S. Gershon β-Adrenoceptor function in human adult skin fibroblasts: a study of manic-depressive illness

Discussion

P. Propping, W. Friedl, J. Hebebrand and K-U. Lentes Genetic studies at the receptor level: investigations in human twins and experimental animals

Discussion

M. Åsberg and A. Wägner Biochemical effects of antidepressant treatment—studies of monoamine metabolites in cerebrospinal fluid and platelet [³H]imipramine binding

Discussion

R.W. Horton, C.L.E. Katona, A.E. Theodorou, A.S. Hale, S.L. Davies, C. Tunnicliffe, Y. Yamaguchi, E.S. Paykel and J.S. Kelly Platelet radioligand binding and neuroendocrine challenge tests in depression

Discussion

D.L. Murphy, C.S. Aulakh and N. A. Garrick How antidepressants work: cautionary conclusions based on clinical and laboratory studies of the longer-term consequences of monoamine oxidase-inhibiting antidepressants

Discussion

S.A. Checkley, T.H. Corn, I.B. Glass, C. Thompson, C. Franey and J. Arendt Neuroendocrine and other studies of the mechanism of antidepressant action of desipramine

Discussion

L.J. Siever, E.F. Coccaro, E. Benjamin, K. Rubinstein and K.L. Davis Adrenergic and serotonergic receptor responsiveness in depression

Discussion

General discussion I

A. Frazer, G. Ordway, J. O’Donnell, P. Vos and B. Wolfe Effect of repeated administration of clenbuterol on the regulation of β-adrenoceptors in the central nervous system of the rat

Discussion

J.M. Weiss and P.G. Simson Depression in an animal model: focus on the locus ceruleus

Discussion

G.W. Kraemer Causes of changes in brain noradrenaline systems and later effects on responses to social stressors in rhesus monkeys: the cascade hypothesis

Discussion

J. Vetulani, L. Antkiewicz-Michaluk, A. Rokosz-Pelc and J. Michaluk Effects of chronically administered antidepressants and electroconvulsive treatment on cerebral neurotransmitter receptors in rodents with ‘model depression’

Discussion

A.R. Green, D.J. Heal and G.M. Goodwin The effects of electroconvulsive therapy and antidepressant drugs on monoamine receptors in rodent brain—similarities and differences

Discussion

General discussion II

Closing remarks

Index of contributors

Subject index

Keywords: MEDICAL / Neuroscience MED057000