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Foundation, Novartis

Acetaldehyde-Related Pathology: Bridging the Trans-Disciplinary Divide

Foundation, Novartis - Acetaldehyde-Related Pathology: Bridging the Trans-Disciplinary Divide, ebook

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ISBN: 9780470511831
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Part of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in cigarette smoke and other pollutants and derived from ingested alcohol, amongst other sources. In the body, acetaldehyde affects several tissues, particularly the brain and liver, causing various diseases, including cancer, alcoholic liver disease and Alzheimer’s.

Acetaldehyde-Related Pathology describes the toxic effects of acetaldehyde at the tissue and cellular levels, reviewing enzyme biochemistry, transgenic mouse models of alcohol dehydrogenase mutants, and the cell-signalling pathways implicated in alcohol-related pathology. It explores the mechanisms of acetaldehyde-induced damage to tissues, often a first step in carcinogenesis, including the oral cavity, the human airway, and the GI tract. The book considers pharmacological strategies and treatments for reducing oral and intestinal acetaldehyde. Acetaldehyde-Related Pathology features in-depth, round-table discussions by an international array of scientists from major laboratories worldwide involved in studies of acetaldehyde-related pathology.

This book is essential reading for anyone interested in the effects of this compound - pathologists, biochemists, toxicologists, cell and molecular biologists.

Keywords: SCIENCE / Life Sciences / Biochemistry SCI007000

Author(s)
Publisher
John Wiley and Sons, Inc.
Publication year
2007
Language
en
Edition
1
Series
Novartis Foundation Symposia
Page amount
286 pages
Category
Natural Sciences
Format
Ebook
eISBN (PDF)
9780470511831
Printed ISBN
9780470057667

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