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Chen, Guodong

Protein and Peptide Mass Spectrometry in Drug Discovery

Chen, Guodong - Protein and Peptide Mass Spectrometry in Drug Discovery, ebook

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The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery

An instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade. Bringing together the work of experts in academia and industry, Protein and Peptide Mass Spectrometry in Drug Discovery highlights current analytical approaches, industry practices, and modern strategies for the characterization of both peptides and proteins in drug discovery.

Illustrating the critical role MS technology plays in characterizing target proteins and protein products, the methods used, ion mobility, and the use of microwave radiation to speed proteolysis, the book also covers important emerging applications for neuroproteomics and antigenic peptides. Placing an emphasis on the pharmaceutical industry, the book stresses practice and applications, presenting real-world examples covering the most recent advances in mass spectrometry, and providing an invaluable resource for pharmaceutical scientists in industry and academia, analytical and bioanalytical chemists, and researchers in protein science and proteomics.

Keywords: pharmaceutical analysis, protein structure, pharmaceutical industry, imaging mass spectrometry, ion mobility, microwave assisted mass spectrometry, peptide interactions, protein interactions, ligand interactions, protein folding, protein unfolding, Proteins & Macromolecules, Mass Spectrometry, Proteins & Macromolecules, Mass Spectrometry

Editor
 
 
Publisher
John Wiley and Sons, Inc.
Publication year
2012
Language
en
Edition
1
Page amount
448 pages
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (ePUB)
9781118116548
Printed ISBN
9780470258170

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