Gunning, Peter
Tropomyosin
1. Introduction and Historical Perspective
Peter Gunning
Section I.. Genes and Their Expression
2. Structure and Evolution of Tropomyosin Genes
Bernadette Vrhovski, Nadine Thézé, Pierre Thiébaud
3. Tropomyosin Exons as Models for Alternative Splicing
Clare Gooding, Christopher W. J. Smith
4. Tropomyosin Gene Expression in Vivo and in Vitro
Galina Schevzov, Geraldine O’Neill
Section II.. Protein Structure
5. Tropomyosin: Function Follows Structure
Sarah E. Hitchcock-DeGregori
6. Dimerization of Tropomyosins
Mario Gimona
Section III.. Role in Muscle Function
7. Cooperative Binding of Tropomyosin to Actin
Larry S. Tobacman
8. Tropomyosin and the Steric Mechanism of Muscle Regulation
William Lehman, Roger Craig
9. Role of Tropomyosin in the Regulation of Contraction in Smooth Muscle
Steve Marston, M. El-Mezgueldi
Section IV. Tropomyosin in Human Disease
10. Tropomyosin as a Regulator of Cancer Cell Transformation
David M. Helfman, Patrick Flynn, Protiti Khan, Ali Saeed
11. The Role of Tropomyosin in Heart Disease
David F. Wieczorek, Ganapathy Jagatheesan, Sudarsan Rajan
12. Tropomyosins in Skeletal Muscle Diseases
Anthony J. Kee, Edna C. Hardeman
13. Tropomyosins in Human Diseases: Ulcerative Colitis
Kiron M. Das, Manisha Bajpai
Section V.. Tropomyosin Directed Regulation of the Cytoskeleton
14. Tropomyosin Function in Yeast
David Pruyne
15. Isoform Sorting of Tropomyosins
Claire Martin, Peter Gunning
16. Human Tropomyosin Isoforms in the Regulation of Cytoskeleton Functions
Jim Jung-Ching Lin, Robbin D. Eppinga, Kerri S. Warren, Keith R. McCrae
Section VI.. Mechanisms of Tropomyosin Function
17. Tropomyosins Regulate the Impact of Actin Binding Proteins on Actin Filaments
Uno Lindberg, Clarence E. Schutt, Robert D. Goldman, Maria Nyåkern-Meazza, Louise Hillberg, Li-Sophie Zhao Rathje, Staffan Grenklo
18. Tropomyosin and ADF/Cofilin as Collaborators and Competitors
Thomas B. Kuhn, James R. Bamburg
19. Caldesmon and the Regulation of Cytoskeletal Functions
C. -L. Albert Wang
20. Tropomyosins as Discriminators of Myosin Function
E. Michael Ostap
21. Tropomodulin/Tropomyosin Interactions Regulate Actin Pointed End Dynamics
Alla S. Kostyukova
Section VII.. Conclusion
22. Emerging Issues for Tropomyosin Structure, Regulation, Function and Pathology
Peter Gunning
Keywords: Biomedicine, Biomedicine general
- Author(s)
- Gunning, Peter
- Publisher
- Springer
- Publication year
- 2008
- Language
- en
- Edition
- 1
- Series
- Advances in Experimental Medicine and Biology
- Page amount
- 323 pages
- Category
- Medicine, Health Care, Mode
- Format
- Ebook
- eISBN (PDF)
- 9780387857664