Köfalvi, Attila

Cannabinoids and the Brain

Cannabinoids and the Brain


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ISBN: 9780387743493
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Table of contents

I.Molecular Biology, Pharmacology, Anatomy, and Physiology of the Endocannabinoid and Related Lipidergic Signaling Systems in the Brain

1. An Historical Introduction to the Endocannabinoid and Endovanilloid Systems
Istvan Nagy, John P. M. White, Cleoper C. Paule, Attila Köfalvi

2. Biosynthesis of Anandamide and 2-Arachidonoylglycerol
Takayuki Sugiura

3. Removal of Endocannabinoids by the Body: Mechanisms and Therapeutic Possibilities
Christopher J. Fowler, Lina Thors

4. Other Cannabimimetic Lipid Signaling Molecules
Heather B. Bradshaw

5. CB1 Cannabinoid Receptors: Molecular Biology, Second Messenger Coupling and Polarized Trafficking in Neurons
Andrew J. Irving, Neil A. McDonald, Tibor Harkany

6. CB2 Cannabinoid Receptors: Molecular, Signaling, and Trafficking Properties
Paul L. Prather

7. CB1 and CB2 Receptor Pharmacology
Roger G. Pertwee

8. Functional Molecular Biology of the TRPV1 Ion Channel
Istvan Nagy, John P. M. White, Cleoper C. Paule, Mervyn Maze, Laszlo Urban

9. Alternative Interacting Sites and Novel Receptors for Cannabinoid Ligands
Attila Köfalvi

10. Anatomical Distribution of Receptors, Ligands and Enzymes in the Brain and in the Spinal Cord: Circuitries and Neurochemistry
Giovanni Marsicano, Rohini Kuner

11. Endocannabinoids at the Synapse: Retrograde Signaling and Presynaptic Plasticity in the Brain
Gregory L. Gerdeman

12. Endocannabinoid Functions in Neurogenesis, Neuronal Migration, and Specification
Tibor Harkany, Manuel Guzmán, Yasmin L. Hurd

II.The Endocannabinoid System in Clinical Neuroscience and Experimental Neuropsychiatry

13. Cannabinoids in the Management of Nausea and Vomiting
Linda A. Parker, Cheryl L. Limebeer

14. Endocannabinoids in Energy Homeostasis and Metabolic Disorders
Isabel Matias, Vincenzo Marzo, Attila Köfalvi

15. Cannabinoids and Neuroprotection
Veronica A. Campbell, Eric J. Downer

16. Neuroinflammation and the Glial Endocannabinoid System
Cristina Benito, Rosa María Tolón, Estefanía Núñez, María Ruth Pazos, Julián Romero

17. Targeting Cannabinoid Receptors in Brain Tumors
Guillermo Velasco, Arkaitz Carracedo, Cristina Blázquez, Mar Lorente, Tania Aguado, Cristina Sánchez, Ismael Galve-Roperh, Manuel Guzmán

18. Cannabinoids for the Control of multiple Sclerosis
Gareth Pryce, Sam J. Jackson, David Baker

19. Endocannabinoids in Alzheimer's Disease
María L. Ceballos

20. The Endocannabinoid System as a Therapeutic Target in Epilepsy
Krisztina Monory, Beat Lutz

II.The Endocannabinoid System in Clinical Neuroscience and Experimental Neuropsychiatry

21. The Endocannabinoid System in the Physiology and Pathology of the Basal Ganglia
Gregory L. Gerdeman, Javier Fernández-Ruiz

22. The Endocannabinoid System is a Major Player in Schizophrenia
Attila Köfalvi, Markus Fritzsche

23. The Cannabinoid Controversy: Cannabinoid Agonists and Antagonists as Potential Novel Therapies for Mood Disorders
Eleni T. Tzavara, John Jeffrey M. Witkin

24. Role of Cannabinoid Receptors in Anxiety Disorders
Aldemar Degroot


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Keywords: TECHNOLOGY & ENGINEERING / Biomedical TEC059000

Publication year
Medicine, Health Care, Mode

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