Acute Myelogenous Leukemia

1. The Leukemia Stem Cell
Zeev Estrov

2. Epigenetic Mechanisms in AML – A Target for Therapy
Yasuhiro Oki, Jean - Pierre J. Issa

3. Chromosomal Translocations in AML: Detection and Prognostic Significance
Nallasivam Palanisamy

4. Chromosomal Deletions in AML
Lalitha Nagarajan

5. Genes Predictive of Outcome and Novel Molecular Classification Schemes in Adult Acute Myeloid Leukemia
Roel G. W. Verhaak, Peter J. M. Valk

6. Receptor Tyrosine Kinase Alterations in AML – Biology and Therapy
Derek L. Stirewalt, Soheil Meshinchi

7. Lineage-Specific Transcription Factor Aberrations in AML
Beatrice U. Mueller, Thomas Pabst

8. Proleukemic RUNX1 and CBFβ Mutations in the Pathogenesis of Acute Leukemia
Michael E. Engel, Scott W. Hiebert

9. Acute Myeloid Leukemia with Mutated Nucleophosmin (NPM1): Molecular, Pathological, and Clinical Features
Brunangelo Falini

10. MicroRNAs: New Players in AML Pathogenesis
Milena S. Nicoloso, Bharti Jasra, George A. Calin

11. Murine Models of Human Acute Myeloid Leukemia
Julie M. Fortier, Timothy A. Graubert

12. Apoptosis in Leukemias: Regulation and Therapeutic Targeting
Ismael Samudio, Marina Konopleva, Bing Carter, Michael Andreeff

13. Acute Promyelocytic Leukemia: A Paradigm for Differentiation Therapy
David Grimwade, Anita R. Mistry, Ellen Solomon, Fabien Guidez

14. Immunotherapy of AML
Gheath Alatrash, Jeffrey J. Molldrem

15. Therapy of Acute Myelogenous Leukemia in Adults
Gautam Borthakur, Elihu E. Estey

Keywords: Medicine & Public Health, Oncology, Hematology