Multiple Testing Procedures with Applications to Genomics

1. Multiple Hypothesis Testing

2. Test Statistics Null Distribution

3. Overview of Multiple Testing Procedures

4. Single-Step Multiple Testing Procedures for Controlling General Type I Error Rates, T(Fvn)

5. Step-Down Multiple Testing Procedures for Controlling the Family-Wise Error Rate

6. Augmentation Multiple Testing Procedures for Controlling Generalized Tail Probability Error Rates

7. Resampling-Based Empirical Bayes multiple Testing Procedures for Controlling Generalized Tail Probability Error Rates

8. Simulation Studies: Assessment of Test Statistics Null Distributions

9. Identification of Differentially Expressed and Co-Expressed Genes in High-Throughput Gene Expression Experiments

10. Multiple Tests of Association with Biological Annotation Metadata

11. HIV-1 Sequence Variation and Viral Replication Capacity

12. Genetic Mapping of Complex Human Traits Using Single Nucleotide Polymorphisms: The ObeLinks Project

13. Software Implementation

DRM-restrictions

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Keywords: SCIENCE / Life Sciences / Biology / General SCI008000