The p53 Tumor Suppressor Pathway and Cancer

1. The p53 Network
Arnold J. Levine, Jill Bargonetti, Gareth L. Bond, Josephine Hoh, Kenan Onel, Michael Overholtzer, Archontoula Stoffel, Angelica K. Teresky, Christine A. Walsh, Shengkan Jin

2. The Three-Dimensional Structure of p53
Elena S. Stavridi, Yentram Huyen, Emily A. Sheston, Thanos D. Halazonetis

3. Transcriptional Activation by p53: Mechanisms and Targeted Genes
Timothy MacLachlan, Wafik El-Deiry

4. Transcriptional Repression by the p53 Tumor Suppressor Protein
Jack T. Zilfou, Maureen E. Murphy

5. Posttranslational Modifications of p53: Upstream Signaling Pathways
Carl W. Anderson, Ettore Appella

6. p53 in Human Cancer — Somatic and Inherited Mutations and Mutation-independent Mechanisms
Ute M. Moll, Nicole Concin

7. MDM2 and MDMX Regulators of p53 Activity
Jamil Momand, Paul Joseph Aspuria, Saori Furuta

8. p53 Family Members: p63 and p73
Elsa R. Flores, Tyler Jacks

9. The Oncogenic Activity of p53 Mutants
Alex Sigal, Varda Rotter

10. Therapeutic Strategies Based on Pharmacological Modulation of p53 Pathway
Andrei V. Gudkov

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Keywords: TECHNOLOGY & ENGINEERING / Biomedical TEC059000