Blondelle, Sylvie E.
Understanding Biology Using Peptides
1. From Tens to Trillions - Advances in Synthetic Combinatorial Chemistry of Peptides, Peptidomimetics and Heterocyclic Compounds Derived from Peptides
Richard A. Houghten
2. Peptides in the Days of Photonics
Christian Renner, Luis Moroder
3. It All Started in Brooklyn, NY, Forty-five Years Ago!
Claudio Toniolo
4. Short Transmembrane Peptide Sequences as Nucleation Sites for Globular Protein Folding
Arianna Rath, Linda Lee, Rachel M. Johnson, Charles M. Deber
5. Synthesis and In Vitro Opioid Activity Profiles of Novel Cyclic Enkephalin Analogs
Peter W. Schiller, Grazyna Weltrowska, Irena Berezowska, Carole Lemieux, Nga N. Chung, Brian C. Wilkes
6. A Photo-Controlled ß-Hairpin
Markus Löweneck, Shou-Liang Dong, Tobias E. Schrader, Wolfgang J. Schreier, Wolfgang Zinth, Luis Moroder, Christian Renner
7. Structure-Function Relationship Studies of Analogs of PTH(1–11) Fragment Containing Combinations of Aib and (aMe)Nle
Andrea Caporale, Nereo Fiori, Elisabetta Schievano, Michael Chorev, Stefano Mammi, Evaristo Peggion
8. Membrane Associated Structure of a Ghrelin Agonist as Determined by NMR
Dale F. Mierke, Andrea Piserchio, John Eynon, Jundong Zhang, John E. Taylor, Heather Halem, Michael D. Culler, Jesse Z. Dong
9. Scaffold, Dendritic and Metal-Assisted Assembly of Collagen-Like Biomaterials
Weibo Cai, Sen Wai Kwok, Joseph P. Taulane, Murray Goodman
10. Positional Scanning for Peptide Secondary Structure by Solid Phase Synthesis with Aza-Amino Acids and Freidinger Lactams
Damien R. Boeglin, Mandar S. Bodas, Fabrice Galaud, William D. Lubell
11. Synthesis of Cyclic Peptides via Transition Metal Catalyzed C-C Bond Formation
Dirk T. S. Rijkers, Hefziba T. Brink, Nourdin Ghalit, Jan Tois, Rob M. J. Liskamp
12. Solid Phase Synthesis of Phosphorylated
David R. Coleman, Kumar K. Kaluarachchi, John S. McMurray
13. Switch on Amyloid ß Peptide Self-Assembly by Enzyme-Triggered Acyl Migration
Sonia Santos, Arunan Chandravarkar, Bhubaneswar Mandal, Richard Mimna, Karine Murat, Lydiane Saucède, Marie-Stephanie Camus, Gabriele Tuchscherer, Manfred Mutter
14. ROMP of Norbornyl Oligopeptides: A Versatile Synthetic Method for Exploring Receptor Topology
Younjoo Lee, Keith Baessler, Nicole S. Sampson
15. Native Chemical Ligation at Aromatic Residues
Sylvie Tchertchian, Fred Opligger, Marianne Paolini, Sonia Manganiello, Sylvain Raimondi, Benoît Depresle, Nicolas Dafflon, Hubert Gaertner, Paolo Botti
16. Robotic Synthesis of Soluble Peptide Arrays
Wen Lin, James G. Boyd
17. Covalent Capture: Application to Peptides Possessing Auxiliary Groups for Extended Chemical Ligation
Nikolett Mihala, Keith Rose
18. Asymmetric Induction on a Racemic Amine by Chiral Dipeptide 5(4
Alessandro Moretto, Cristina Peggion, Fernando Formaggio, Marco Crisma, Bernard Kaptein, Quirinus B. Broxterman, Claudio Toniolo
19. Poly(ethylene glycol) (PEG) Modifications and Conformational Analysis of Thymosin a 1
Keliang Liu, Jiankun Qie, Jinbo Ma, Liangyou Wang, Wenxia Zhou, Chunhui Qi, Xiunan Zhao, Jianquan Zheng, Sijian Dong
20. Suppression of Side Reactions Associated with Use of the Benzyloxymethyl Group on Histidine
Kumiko Yoshizawa-Kumagaye, Takehiro Ishizu, Shuji Isaka, Masaji Tamura, Rumi Okihara, Yuji Nishiuchi, Terutoshi Kimura
21. Peptide Synthesis in Water: 2-(4-Sulfophenylsulfonyl)ethoxycarbonyl Group and Coupling Reagents
Keiko Hojo, Mitsuko Maeda, Koichi Kawasaki
22. Efficient Synthesis in Solid-Phase of Freidinger-like Lactams by Microwave Irradiation
Teresa Lama, Pietro Campiglia, Luigia Auriemma, Isabel Gomez-Monterrey, Alfonso Carotenuto, Ettore Novellino, Paolo Grieco
23. Synthesis of Monocyte Chemoattractant Protein 1 (MCP-1) Analogs via Native Chemical Ligation
Tami L. Raguse, Nicole Stowell, Reannon Holland, Thomas Bodenstine, Steven C. Pomerantz, Jennifer F. Nemeth, Anuk Das, Marian Kruszynski, George A. Heavner
24. NMR Analysis of a Multi-domain Peptide of the
Racha Estephan, Jacqueline Englander, Boris Arshava, Jeffrey M. Becker, Fred Naider
25. Further Studies on an Alternative Approach to Prepare Esterified Protected Peptides under Mild Conditions
Patrícia B. Proti, Pedro V. Oliveira, M. Terêsa M. Miranda
26. A Long Range S,N-Acyl Migration by Silver Ion Assistance in Thioester Ligation
Yi-An Lu, James P. Tam
27. The C-Terminal Fragment of Acanthoscurrin is a Difficult Sequence
César Remuzgo, Gustavo F. S. Andrade, Maria L. A. Temperini, Sirlei Daffre, M. Terêsa M. Miranda
28. A Novel Approach to Resin-based Cysteine Alkylation
Bin Yang, Richard D. DiMarchi
29. Deprotection of the
Katharine M. Harris, Robert J. Hondal
30. Overcoming Challenges in Automated Long Peptide Synthesis — A Multi-pronged Approach
Yingwei He, Guodi Lu, John Mountzouris, Chun Wu
31. Synthesis and Biological Evaluation of Antagonist Analogs of the Peptide Hormone Oxytocin
Jake L. Stymiest, Bryan F. Mitchell, Susan Wong, John C. Vederas
32. Development of Wang Resin Supported Evans-type Oxazolidinone for Asymmetric Reaction
Tomoya Kotake, Yoshio Hayashi, S. Rajesh, Tooru Kimura, Yoshiaki Kiso
33. A Convenient Synthetic Method for Monodehydro-2,5-diketopiperazines
Yoshio Hayashi, Akiko Oda, Yuri Yamazaki, Yuka Okuno, Yoshiaki Kiso
34. Solid-Phase Synthesis of Azole-Based Peptides and Peptidomimetics
Eric Biron, Horst Kessler
35. Efficient Synthesis of
Eric Biron, Jayanta Chatterjee, Horst Kessler
36. The “
Youhei Sohma, Maiko Kimura, Yousuke Chiyomori, Yoshio Hayashi, Atsuhiko Taniguchi, Masato Sasaki, Tooru Kimura, Yoshiaki Kiso
37. The “
Yousuke Chiyomori, Youhei Sohma, Maiko Kimura, Yoshio Hayashi, Fukue Fukao, Atsuhiko Taniguchi, Tooru Kimura, Yoshiaki Kiso
38. Enhancing Atom Economy of SPS: Recoverable and Reusable Building Blocks for Depsipeptide Synthesis
Jan Spengler, Javier Ruíz-Rodríguez, Tommaso Cupido, Klaus Burger, Fernando Albericio
39. 1-N-Methyl-Histidine as a Side-Product in Backbone N-Methylated PTH Analogs
Zhanna Potetinova, Gordon E. Willick
40. Combinatorial Approach in the Synthesis of a Small Library of ß-Turn Structures Based on Thiazolidine Moiety
Alfonso Carotenuto, Teresa Lama, Orazio Mazzoni, Pietro Campiglia, Ettore Novellino, Alessia Bertamino, Maria V. Diurno, Isabel Gomez-Monterrey, Luigia Auriemma, Paolo Grieco
41. Solid-Phase Peptide Synthesis Using ChemMatrix®, a Polyethylenglycol (PEG)-based Solid
Fernando Albericio, Nuria Bayo, Silvia A. Camperi, Osvaldo Cascone, Simon Côté, Luis J. Cruz, Abdelhamid Errachid, Robert Furic, Fayna García-Martín, Yesica García-Ramos, Nancy B. Iannucci, Mariela M. Marani, Mateu Pla-Roca, Martina Quintanar-Audelo, Josep Samitier, Judit Tulla-Puche
42.
Albert Isidro-Llobet, Pilar E. López, Judit Guasch-Camell, Mercedes álvarez, Fernando Albericio
43. Synthesis and NMR Analysis of CCR5 and CXCR4 Peptides Containing Tyrosine Sulfate
Tatsuya Inui, Patricia Cano-Sanchez, Boris Arshava, Inbal Ayzenshtat, Jacob Anglister, Fred Naider
44. Steroid-Peptide Conjugates
Witold A. Neugebauer, Jérôme Côté, Audrey Fortier, Ghassan Bkaily, Levon Avedanian, Danielle Jaques, Fernand Gobeil
45. Influence of Natural Loop Residues or Oligolysines on the Biophysical Properties of Transmembrane Domains of a G Protein-Coupled Receptor
Patricia Cano-Sanchez, Tatsuya Inui, Beatrice Severino, V. V. Suresh Babu, Boris Arshava, Jeffrey M. Becker, Fred Naider
46. Design, Synthesis and Analysis of Constrained B-Cell Epitope from HER-2 Protein
Sharad V. Rawale, Pravin T. P. Kaumaya
47. Synthesis of the Four Stereoisomers of N-Fmoc-O-t-Bu-4,4,4- trifluorothreonine
Zhong-Xing Jiang, Yihua Bruce Yu
48. Synthesis of
Aimin Song, Lucy Wu, Xiaobing Wang, Kit S. Lam
49. A MS-based Encoding Method for OBOC Combinatorial Branched Peptide Libraries
Xiaobing Wang, Kit S. Lam
50. Sequential Chemical Ligation for Polypeptide Synthesis by the Combination of the Thioester Method and the Extended Chemical Ligation Using a Photoremovable Auxiliary
Toru Kawakami, Masahiro Tsuchiya, Ken’ichiroh Nakamura, Saburo Aimoto
51. Solid-Phase Synthesis of a Mucin Glycopeptide Segment from CD43 for NMR and Crystallization Studies
Mian Liu, George Barany, David Live
52. SPPS of Bacterial Addressed Peptides and PNAs Overcoming the Resistance against Antibiotics
Rüdiger Pipkorn, Waldemar Waldeck, Klaus Braun
53. Convergent Synthesis of the Cysteine-rich Mdm2 RING Finger Domain
Zoe Vasileiou, Dimitrios Gatos, Kleomenis Barlos
54. Evaluation of Polyamide-Polystyrene Block Polymers in Peptide Synthesis and Biochemistry
Spyros Markos, Antonios Saravanos, Michael Batistatos, Alexios Aletras, Dimitrios Gatos, Kleomenis Barlos
55. New Nomenclature for Complex Cyclopeptides
Jan Spengler, José-Carlos Jiménez, Klaus Burger, Ernest Giralt, Fernando Albericio
56. New Approaches for Native Chemical Ligation
Dana Baas, Daniel G. Mullen, George Barany
57. Microwave-Assisted Solid-Phase Peptide Synthesis (MW-SPPS) on CLEAR Supports
Anne L. Carenbauer, Matthew R. Cecil, Andrzej Czerwinski, Krzysztof Darlak, Miroslawa Darlak, DeAnna Wiegandt Long, Francisco Valenzuela, George Barany
58. Microwave Assisted Peptide Synthesis — A Tool to Replace Classical SPPS?
Andreas Rybka, Hans-Georg Frank
59. Fast and Versatile Peptide Backbone Modifications Using Microwave Energy
Daniel Raichman, Gerardo Byk
60. Microwave-Assisted Synthesis of Multivalent Dendrimeric Peptides using Cycloaddition Reaction (‘Click’) Chemistry
Dirk T. S. Rijkers, G. Wilma Esse, Remco Merkx, Arwin J. Brouwer, Hans J. F. Jacobs, Roland J. Pieters, Rob M. J. Liskamp
61. Efficient Synthesis of Disulfide Bridge Containing Peptides: Melanin Concentrating Hormone (MCH) and Brain Natriuretic Peptide (BNP)
Jianjun Jiang, Brian D. Dayton, Sevan J. Brodjian, Bryan C. Tieman, Susan E. Brophy, Paul L. Richardson
62. Rapid Solution-phase Synthesis of a 20-mer Peptide According to the DioRaSSP® Method
Ivo F. Eggen, Frits T. Bakelaar, Paul B. W. Kortenaar, Knut Adermann, Wolf-Georg Forssmann, Axel Schulz
63. A New Efficient Post-Assembly Strategy for the Synthesis of Sulfated Peptides
John A. W. Kruijtzer, Johan Kemmink, Rob M. J. Liskamp
64. Auxiliary Group-Assisted Peptide Thioester Preparation Based on On-resin
Megumi Sumida, Ken’ichiroh Nakamura, Toru Kawakami, Thomas Vorherr, Saburo Aimoto
65. Determination of an Optimal Solid Support for Use with Microwave-Assisted Solid-Phase Peptide Synthesis
Sandra C. Vigil-Cruz, Angela M. Peck, Jane V. Aldrich
66. Efficient Recombinant Production of the 16 Amino Acid Peptide AOD9604
Allan W. Hey, Angelo Guidolin, Reza Zareie, Kathryn Smith, Ela Knapik, Stan Bastiras
67. Chemical Synthesis of the Gsti Protein by a NCL Method on a X-Met Site
Daniela Marasco, Angela Saporito, Paolo Botti, Eduardo Patriarca, Rossella Fasulo, Alessandro Spasiano, Carlo Pedone, Ettore Benedetti, Menotti Ruvo
68. N,O-Acyl Shifts: Unexpected Side-Reaction and Beneficial Tool in Fmoc-Chemistry
Louis A. Carpino, Calin D. Sferdean, Irene Coin, Sandra Tremmel, Eberhard Krause, Michael Bienert, Michael Beyermann
69. Magnetic CLEAR Beads for Solid-Phase Synthesis of Peptides and Affinity Ligands
Pottayil G. Sasikumar, Maria Kempe
70. An Efficient and Facile Synthesis of Tyrosine-Sulfate-Containing Peptides: Synthesis of the N-Terminal Peptide of CCR5 and Its Analog
Hasmik Sargsyan, Boris Arshava, Patricia Cano, Tatsuya Inui, Jacob Anglister, Fred Naider
71. Interaction of DPH with the Local Anesthetic Receptor Site in D1-S6 of the Na
Bih-Show Lou, Ta-Hsien Lin
72. The Structural Determinants of GPCR Binding and Activation: Insights from Mutagenesis and Molecular Modeling Studies of the Human Angiotensin II Type 1 (hAT1) Receptor
Marie-Eve Beaulieu, Pierre Lavigne, Emanuel Escher
73. Protein Epitope Mimetics A New Approach to Target Protein-Protein Interactions
Frank Otto Gombert, Jan Willem Vrijbloed, Daniel Obrecht
74. Application of Phenylphosphate Mimetics to the Design and Synthesis of Olefin Metathesis-Derived Grb2 SH2 Domain-Binding Macrocycles
Sang-Uk Kang, Zhen-Dan Shi1, Rajeshri Kariki1, Jason Phan, Karen M. Worthy, Lakshman K. Bindu, Marc Nicklaus, David S. Waugh, Robert J. Fisher, Terrence R. Burke
75. Radiolabeled Peptides as CXCR4 Ligands
Ettore Benedetti, Giancarlo Morelli, Raffaella Moglie, Stefania Luca, Luigi Aloj, Andrea Ciarmiello, Secondo Lastoria, Claudio Arra, Amelia D’Alessio, Laura Tarallo
76. Aza-peptides with Multiple Aza-amino Acids, Synthesis and Preliminary Conformational Analysis of Glu-azaAla-Ala-azaAla-Leu-azaAla-Lys-azaAla-NH
Damien R. Boeglin, Mallem H. V. Ramana Rao, Jean-Philippe Demers, William D. Lubell
77. Design and Synthesis of Bicyclic Internal
Byoung J. Min, Xuyuan Gu, Ravil R. Petrov, Yeon Sun Lee, Victor J. Hruby
78. Synthesis and Incorporation of Freidinger Lactam Analogs in GHRP-6
Fabrice Galaud, Annie Demers, Huy Ong, William D. Lubell
79. Microwave-assisted Synthesis of
Ilaria Paolini, Francesca Nuti, Giuseppina Sabatino, Mario Chelli, Anna M. Papini
80. Parallel Solid-Phase Synthesis of Mucin-Like Glycopeptides from an a-GalN
Mian Liu, David Live, George Barany
81. Synthesis of Silyl Ether Linkers for Solid-Phase Peptide Synthesis
Cassidy M. Dobson, George Barany, Rita S. Majerle
82. Synthetic Routes to, and Mechanistic Understanding of, Dithiasuccinoyl (Dts)-Amines and Chlorocarbonyl Carbamoyl Disulfanes
Michael J. Barany, Megan M. Corey, Michael C. Hanson, Rita S. Majerle, Robert P. Hammer, George Barany
83. Peptide-Derived (Sulfonyl)Azides as Versatile Synthons in Chemoselective Bioconjugations
Remco Merkx, Dirk T. S. Rijkers, Arwin J. Brouwer, Johan Kemmink, Rob M. J. Liskamp
84. Chemically Synthesized Annexin-A5-Based Probes for Molecular Imaging
Cheng-Bin Yim, Anouk Dirksen, Chris P. M. Reutelingsperger, Tilman M. Hackeng
85. Unequivocal Synthesis of (
Ayumu Niida, Shinya Oishi, Makiko Mizumoto, Yoshikazu Sasaki, Kenji Tomita, Hirokazu Tamamura, Akira Otaka, Tomohiro Terada, Ken-ichi Inui, Nobutaka Fujii
86. Development of New Photoremovable Amino Protecting Group and its Application toward Chemical Synthesis of 7TM-GPCR
Satoshi Ueda, Akira Otaka, Hirokazu Tamamura, Nobutaka Fujii
87. Multivalent Peptide Dendrimers: Native Chemical Ligation as a Synthetic Tool
Hinke Malda, Tilman M. Hackeng, Marcel H. P. Genderen, Egbert W. Meijer
88. Synthesis and Use of C-terminally Biotinylated Peptidomimetics with High Grb2 SH2 Domain-binding Affinity
Zhen-Dan Shi, Benedetta Peruzzi, Pathirage G. Dharmawardana, Tiffany Leech, Ettore Appella, Karen M. Worthy, Lakshman K. Bindu, Robert J. Fisher, Donald P. Bottaro, Terrence R. Burke
89. Total Solid Phase Synthesis of a Marine Cyclodepsipeptide IB-01212
Luiz J. Cruz, Marta Martínez, Julia Pérez, Marta Trujillo, Librada M. Cañedo, Ricard Rodríguez, Ernest Giralt, Fernando Albericio
90. Interference with Protein-Protein Interactions Involved in Protease Inhibitor Complex Formation
Dirk-Jan Zoelen, Maarten R. Egmond, Roland J. Pieters, Rob M. J. Liskamp
91. Sequence-Enabled Reassembly (SEER) Peptides for the Detection of DNA Sequences
Aik T. Ooi, Cliff I. Stains, Jason R. Porter, Indraneel Ghosh, David J. Segal
92. A Mild Acidic Method for the Selective Deprotection of
Jonathan P. May, David M. Perrin
93. Enantiomerically Pure H-Arg(Z)
Fritz Dick, Juergen Gerhardt, Barbara Jakobi, Beat Sax, Joachim Schwindling, Christian Staehelin
94. Chlorotrityl Chloride (CTC) Resin as a Convenient Reusable Protecting Group
Fayna GarcÍa-MartÍn, Nuria Bayo, Luis J. Cruz, James Bohling, Fernando Albericio
95. Synthesis and Purification of Multiphosphorylated Peptides
Vladimir V. Kalashnikov, Yongping Tang, Jeanick H. Pascal
96. Dealing with the Aggregation Problem of Polyglutamine Peptides: Synthesis Strategies
Myriam Létourneau, Martin Viau, Ariane Sirois, Yvan Boulanger, Alain Fournier
97. Synthesis and Biological Assessment of Insulin-Like Analogs with Differential Activity at the Insulin and IGF-1 Receptors
Richard D. DiMarchi, Jie Han, Amy Hoffman, Vasily M. Gelfanov, Wayne Kohn, Radmila Micanovic, John P. Mayer
98. Biosynthesis of the Cyclotide Kalata B1 using Protein Splicing Tools
Richard Kimura, Krish Krishnan, Julio A. Camarero
99. Exploration and Elaboration of Reported Insulin Superagonism through Site-Selective Replacement at TyrB26
David L. Smiley, Ma Boaquan, Vasily M. Gelfanov, Richard D. DiMarchi
100. Synthesis of an RNase B 30—124 Glycoform by Native Chemical Ligation
Christian Piontek, Stefano Mezzato, Daniel Varon, Nelson Lombana, Manuela Schaffrath, Andreas Martin, Franz-Xaver Schmid, Carlo Unverzagt
101. Threaded Rings and Complex Topologies in Antimicrobial Peptides: Nature’s Engineering Templates
David J. Craik, K. Johan Rosengren, Lillian Sando, Shane S. Simonsen
102. A Minimalist Approach to Antimicrobial Proteins with Thionin as a Template
Miquel Vila-Perelló, Sabrina Tognon, Andrea Sánchez-Vallet, Antonio Molina, David Andreu
103. Discovering Additional Chemical and Biological Functions for 3-Oxo-
Gunnar F. Kaufmann, Rafaella Sartorio, Sang-Hyeup Lee, Claude J. Rogers, Michael M. Meijler, Jason A. Moss, Bruce Clapham, Andrew P. Brogan, Tobin J. Dickerson, Kim D. Janda
104. Comparing Antimicrobial and Membrane Permeabilizing Activity of Peptides Derived from Human Cationic Proteins
Susana Sánchez-Gómez, Guillermo MartÍnez Tejada, José Leiva-Leon, Ignacio Moriyón, Dagmar Zweytick, Karl Lohner, Sylvie E. Blondelle
105. Preliminary NMR Analysis of ProP440–500 the C-Terminal Cytoplasmic Domain of Bacterial Osmosensory Protein ProP
David L. Zoetewey, David N. M. Jones, Janet M. Wood, Robert S. Hodges
106. Synthesis and Conformation of Analogs of the Antiviral Peptide Halovir A
Andrea Bona, Cristina Peggion, Fernando Formaggio, Bernard Kaptein, Quirinus B. Broxterman, Claudio Toniolo
107. Total Synthesis in Solution and Preliminary Conformational Analysis of TOAC-Labeled Alamethicin F50/5 Analogs
Micha Jost, Cristina Peggion, Fernando Formaggio, Claudio Toniolo
108. A Lipid Monolayer Made Permeable to Tl(I) Ions by the Lipopeptaibol Trichogin GA IV
Chiara Baldini, Cristina Peggion, Ester Falletta, Maria Rosa Moncelli, Rolando Guidelli, Claudio Toniolo
109. A Universal Influenza B Peptide Vaccine
Paolo Ingallinella, Elisabetta Bianchi, Xiaoping Liang, Marco Finotto, Michael Chastain, Jiang Fan, Tong-Ming Fu, Hong Chang Song, Melanie Horton, Daniel Freed, Walter Manger, Emily Wen, Li Shi, Roxana Ionescu, Colleen Price, Marc Wenger, Emilio Emini, Riccardo Cortese, Gennaro Ciliberto, John Shiver, Antonello Pessi
110. Design, Synthesis and Analysis of a Cysteine-Deleted Analog of the Antimicrobial Peptide Tachyplesin-I
Deborah L. Heyl, Kiran Kumar Gottipati, Sreeja Sreekumar, Sathan Thennarasu, Ayyalusamy Ramamoorthy
111. Progress toward Total Solid-Phase Synthesis of Cyclic Lipodepsipeptide Antibiotic Fusaricidin A
Rekha Rawat, Ralph T. Martello, Pierre Y. Jean-Charles, Predrag Cudic
112. Biological and Structural Characterization of a New Linear Gomesin Analog
Marcos A. Fázio, Laurence Jouvensal, Françoise Vovelle, Philippe Bulet, M. Terêsa M. Miranda, Sirlei Daffre, Antonio Miranda
113. Monomeric Analogs of Halocidin
Xavier Doisy
114. Fragment of Human Lysozyme Conjugated on the N-terminus and Displaying Antibacterial Properties
Xavier Doisy
115. Synthesis and Raman Spectroscopy Studies of the Antimicrobial Peptide Cecropin B2
Susanne Ladefoged Nielsen, Xavier Doisy
116. Alamethicin Interaction with Lipid Membranes: A Spectroscopic Study on Synthetic Analogs
Lorenzo Stella, Marcello Burattini, Claudia Mazzuca, Antonio Palleschi, Mariano Venanzi, Cristina Peggion, Claudio Toniolo
117. Design of Bactericidal Self-Assembling Cyclic
Shai Rahimipour, Leila Motiei, Reza M. Ghadiri
118. HB-50: A Pre-Clinical Study of a Prophylactic for Wound Infection
Scott M. Harris, Lijuan Zhang, Jody Parente, George T. Rodeheaver, Timothy J. Falla
119. Designer Multifunctional Antimicrobial Peptides Kill Fluoroquinolone-Resistant Clinical Isolates
Laszlo Otvos, John D. Wade, Feng Lin, Barry A. Condie, Christine Snyder, Jorg Hanrieder, Ralf Hoffmann
120. Solution Structures of Stomoxyn and Spinigerin, Two Antimicrobial Peptides from Insects
Celine Landon, Herve Meudal, Nathalie Boulanger, Philippe Bulet, Reto Stöcklin, Françoise Vovelle
121. Rational Design of
Yuxin Chen, Michael Guarnieri, Michael Vasil, Robert S. Hodges
122. Dimer Formation of Novel Cationic Antimicrobial Peptides in Membrane Environments
Evgenia Glukhov, Charles M. Deber
123. Enzymatic Incorporation of Prenyl Azides into Peptides and Proteins: Tools for Selective Protein Labeling
Juhua Xu, Stepan Lenevich, Jason Boggs, Daniel G. Mullen, George Barany, Mark D. Distefano
124.
Michael R. Carrasco
125. Improved Synthesis of 5-hydroxylysine (Hyl) Derivatives
Mare Cudic, Janelle L. Lauer-Fields, Gregg B. Fields
126. Synthesis and Biological Assessment of Sulfonic Acid-Based Glucagon Antagonists
Bin Yang, Vasily M. Gelfanov, Richard D. DiMarchi
127. Thioester Bond Liability: Study on Natural Influenza and Model Acylpeptides
Marina V. Serebryakova, Larisa V. Kordyukova, Boris V. Vaskovsky, Ludmila A. Baratova
128. Chemical Synthesis of MUC2 Tandem Repeat Model Carrying Multiple
Hironobu Hojo, Yoshiyuki Matsumoto, Yoshiaki Nakahara1, Yusuke Suzuki, Minoru Suzuki, Akemi Suzuki
129. Site Specific Introduction of Unnatural Amino Acids at Sites Critical to Insulin Receptor Recognition and Biological Activity
Beili Quan, David L. Smiley, Vasily M. Gelfanov, Richard D. DiMarchi
130. Target-Based Proteolytic Profiling for Characterizing Cancer Progression
Janelle L. Lauer-Fields, Dmitriy Minond, Diane Baronas-Lowell, Michael J. Chalmers, Scott A. Busby, Patrick R. Griffin, Hideaki Nagase, Gregg B. Fields
131. From Simple Consensus Peptides to High Affinity Ligands: A Stepwise Diversity Oriented Strategy for the Acquisition of Potent Signaling Inhibitors
David S. Lawrence
132. Cyclic Modular ß-Sheets
James S. Nowick, Justin O. Brower, Omid Khakshoor, Wade A. Russu, R. Jeremy Woods
133. Apolipoprotein A-I Mimetic Peptides
G. M. Anantharamaiah, Mohamad Navab, Sreenivas T. Reddy, Susan Hama, Greg Hough, Mayakonda N. Palgunachari, Manjula Chaddha, Geeta Datta, David W. Garber, Alan M. Fogelman
134. Understanding BBB Transport using Glycosylated Enkephalins and Endorphins
Dhana Muthu, Isabel Alves, Charles M. Keyari, Larisa Yeomans, Richard D. Egleton, Jean M. Bidlack, Henry I. Yamamura, Victor J. Hruby, Edward J. Bilsky, Robin Polt
135. Design and Study of Novel Peptide Inhibitors against the SARS-Coronavirus Spike Protein
Zhe Yan, Brian Tripet, Robert S. Hodges
136. Screening Biosynthetic Peptide Libraries for Antimicrobial Activity
Lisa O. Nilsson, Mostafa Louassini, Ernesto Abel-Santos
137. Cellular Delivery and Design of Proprotein Convertase Inhibitors
Ajoy Basak, Xiaolei Hao, Ying Feng, Dayani Mohottalage, Farzaneh Lotfipour, Sarmistha Basak
138. Mechanism of Interaction between the (17–31) Binding Domain of PTH and the PTH Receptor
Thomas Dean, Ashok Khatri, Zhanna Potetinova, Gordon Willick, Thomas J. Gardella
139. [3,3]-Sigmatropic Rearrangments, and Chiral Aziridines for the Asymmetric Synthesis of Novel Amino Acids
Hongchang Qu, Lu Liu, Xuyuan Gu, Victor J. Hruby
140. A Library of Cysteine-Biotine Derivatives Useful for Pretargeting Avidin-Biotin Radioimmunoscintigraphy
Cristina Bolzati, Andrea Caporale, Davide Carta, Liliana Cofano, Elisabetta Schievano, Francesco Tisato, Fiorenzo Refosco, Evaristo Peggion, Giuliano Bandoli
141. A Methionine Scan of Region [168–176] of the Parathyroid Hormone Receptor 1 — The “Magnet Effect”
Angela Wittelsberger, Beena E. Thomas, Dale F. Mierke, Michael Rosenblatt
142. A New Approach to the Synthesis of Policyclic Dipeptide Derivatives as Potential Antitumoral Agents
Teresa Lama, Orazio Mazzoni, Pietro Campiglia, Alessia Bertamino, Ettore Novellino, Maria V. Diurno, Isabel Gomez-Monterrey, Antonio Mazzella Bosco, Paolo Grieco
143. A Purification Strategy for Synthetic Peptides that Utilizes pH to Optimize Selectivity
Andrew F. Coffey, Linda L. Lloyd, Keeley J. Mapp, Louise E. Rochell, Alasdair MacDonald
144. Agonist Activation of the Angiotensin II Type 1 Receptor Alters the Spatial Proximity of Transmembrane Domain 7 to the Ligand Binding Pocket
Dany Fillion, Gaétan Guillemette, Richard Leduc, Emanuel Escher
145. An Asymmetric Synthesis of (
Karolien Rompaey, Isabelle Eynde, Steven Ballet, Dirk Tourwé
146. Analogs of Multifunctional Ligands for Opioid and CCK Receptors
Ekaphol Wooden, Vinod Kulkarni, Yeon S. Lee, Richard S. Agnes, Christine Salibay, Peg Davis, Shou-Wu Ma, Josephine Lai, Frank Porreca, Victor J. Hruby
147. Antigen Effects of Peptide Nucleic Acids on HIF-1a Expression
Zhanna Zhilina, Amy Ziemba, Lenka Stankova, Stacey Wood, Meghan Boros, Scot Ebbinghaus
148. Novel Glyco-lipid-arsenicals (III) with Anti-proliferative Effects on MCF-7 Human Breast Cancer Cells
Norbert Wimmer, Jodie A. Robinson, Nagaraj Gopisetty-Venkatta, Sarah J. Roberts-Thomson, Gregory R. Monteith, Istvan Toth
149. Antisense PNA and PNA-peptide Conjugates for the Modulation of ß-globin Gene Splicing
Alessandra Romanelli, Soccorsa Pensato, Erminia Niola, Giordana Feriotto, Francesca Salvatori, Giulia Breveglieri, Laura Zaccaro, Michele Saviano, Roberto Gambari, Carlo Pedone, Ettore Benedetti
150. ß-Amino Acid Analogs of an Insect Neuropeptide
Pawel Zubrzak, Howard J. Williams, Geoffrey M. Coast, Gloria Reyes-Rangel, Eusebio Juaristi, Janusz Zabrocki, Allison Strey, Ronald J. Nachman
151. Branched Neurotensin for Tumor Targeting
Chiara Falciani, Monica Fabbrini, Barbara Lelli, Luisa Lozzi, Alessandro Pini, Luisa Bracci
152. CCK/MSH Analogs and Derivatives for Imaging and Incorporation in Multimeric Ligands
Rajesh Sankaranarayanan, Fang Gao, Jatinder S. Josan, Heather Handl, Josef Vagner, Robert J. Gillies, Victor J. Hruby
153. Cellular Uptake of Pyrrolidine-Based Oxy-Peptide Nucleic Acid
Mizuki Kitamatsu, Rino Matsuzaki, Masahiko Sisido
154. Chemical Biology and Biomedical Application of Synthetic Molecules Targeted to Apoptosis Regulated by the Bcl-2 Family
Jun Wang, Dongxiang Liu, Krishna Kumar, Aihua Nie, Yohichi Kumaki, Pak-Nei Hon, R. Wayne Fritzsche, Jing An, John C. Reed, Ziwei Huang
155. Comparative Immunogenicity of Common and Rare HIV Mutant Peptides
Sylvie E. Blondelle, Rosa Moya, Kim Schroder, Darcy B. Wilson
156. Conformational Studies of Agouti-Related Protein (AGRP)-Melanocortin Chimeric Peptides
Andrzej Wilczynski, Krista R. Wilson, Joseph W. Scott, Arthur S. Edison, Carrie Haskell-Luevano
157. C-Terminal Ether Analogs of NN703
Kjeld Madsen, Peter Andersen, Michael Ankersen, Bernd Peschke, Birgit Sehested, Jan Soerensen
158. Cyclic Statine-based Peptides as Inhibitors of ß-Secretase
Alessandra Barazza, Marion Götz, Christian Renner, Michael Willem, Luis Moroder
159. Design and Structure Determination of a Selenium Labeled Antimicrobial Peptide
Xiaomei Zhou, Phat L. Tran, Joe Fralick, Ted W. Reid
160. Design and Synthesis of Encoded One-bead One-compound Peptidomimetic Libraries for Identification of a
Ruiwu Liu, Li Peng, Jan Marik, Kit S. Lam
161. Design and Synthesis of Histone Deacetylase Inhibitors by Side Chain Modification of 2-Amino-(n-1)-alkenoic Acids
Mohammed P. I. Bhuiyan, Tamaki Kato, Norikazu Nishino
162. Design of a Library of Histone Deacetylase Inhibitors Based on Chlamydocin
Norikazu Nishino, Mohammed P. I. Bhuiyan, Yoshinori Hirashima, Louis A. Watanabe, Priti Soni, Tamaki Kato, Tomonori Nishino, Minoru Yoshida
163. Design of an Antibody for Early Detection of Ovarian Cancer
Danielle Carbin, Sharad Rawale, Carl Morrison, Jeffrey Fowler, Larry Maxwell, Pravin T. P. Kaumaya
164. Design, Synthesis and Applications of Cell-penetrant Peptides as Signal Transduction Modulators
John Howl, Michelle Farquhar, Sarah Jones
165. Novel MTII/AGRP Hybrid Analogs that Lead to Selective Ligands for the Human Melanocortin Receptors
Minying Cai, Alexander Mayorov, Kevin Chandler, Christopher Cabello, Dustin Tanaka, Dev Trivedi, Victor J. Hruby
166. Design, Synthesis, and Evaluation of Gluten Peptide Analogs as Selective Inhibitors of Human TG2
Olga Fierro, Stefania Albrizio, Alfonso Carotenuto, Gabriella Caliendo, Daniela Guarino, Paolo Grieco, Pietro Campiglia, Teresa Lama, Ettore Novellino
167. Novel Blue- and Red-Shifted Internally Quenched Fluorogenic Substrates for Continuous Monitoring of SARS-CoV 3CL
Pamela Hamill, Martin Richer, Derek Hudson, Hongyan Xu, François Jean
168. Discovery and Optimization of a TRAIL R2 Agonist for Cancer Therapy
Yvonne M. Angell, Ashok Bhandari, Anjan Chakrabarti, M. Nuria Francisco, Amy N. Duguay, Brian T. Frederick, Karen Leu, Kerstin Leuther, Xianfeng Li, Kalyani Penta, Sunila Piplani, Reuben Sana, Erik A. Whitehorn, Pete J. Schatz, Kevin Yin, Christopher P. Holmes
169. Development of Peptide Vaccines against HPV-16 Associated Cervical Cancer and Group A Streptococci
Peter M. Moyle, Aniko Horváth, Levente Karpati, Colleen Olive, Nadia Barozzi, Norbert Wimmer, Michael Good, Istvan Toth
170. Disulfide as a Constraint to Build Super Potent and Selective Melanocortin-4 Receptor (MC4R) Agonists
Zeng Yan Liang, David Flora, Patrick Edwards, David L. Smiley, Paul J. Emmerson, Hansen M. Hsiung, Robert Gadski, JeAnne Hertel, Mark L. Heiman, Saba Husain, Thomas P. O’Brien, Steven D. Kahl, Lianshan Zhang, Richard D. DiMarchi, John P. Mayer
171. Effect of Dimerization and Tetramerization on the Potency of HIV-1 Integrase Inhibitory Peptides
Krzysztof Krajewski, Christophe Marchand, Yves Pommier, Peter P. Roller
172. The Effects of Stable Bradykinin Receptor 2 Agonist B9972 on Pulmonary Vasculature
Laimute Taraseviciene-Stewart, John M. Stewart, Lajos Gera, Nana Burns, Robertas Scerbavicius, Norbert F. Voelkel
173. Etk/Bmx Tyrosine Kinase Peptide Substrates and Inhibitors Derived from the Autophosphorylation Site of the Enzyme
Ching-Yi Hsieh, Jan Marik, Jenny Kung, Coleen Sweeney, Kit S. Lam, Hsing-Jien Kung
174. Fluorescence Resonance Energy Transfer Substrates for Determining Cathepsin B pH Specificity
Paolo Ruzza, Luigi Quintieri, Alessio Osler, Andrea Calderan, Barbara Biondi, Maura Floreani, Andrea Guiotto, Gianfranco Borin
175. Ghrelin Attenuates Burn-induced Cachexia
Ambikaipakan Balasubramaniam, Rashika Joshi, Chunhua Su, Lou Ann Friend, James H. James
176. High Affinity High Specificity a4ß1 Integrin Targeting Peptidomimetics for Lymphoid Cancers
Li Peng, Ruiwu Liu, Xiaobing Wang, Jan Marik, Yoshikazu Takada, Kit S. Lam
177. Highly
Eric Biron, Daniel Langenegger, Daniel Hoyer, Horst Kessler
178. Highly Sensitivity FRET Substrate for Assay of HCV Protease
Xiaohe Tong, Ling Sheng, Xiaofen Zhong, Yi Tang, Junge Lu, Zhenjun Diwu, Anita Hong
179. Identification and Characterization of Synthetic Peptide Substrates and Small Molecule Inhibitors of Non Receptor Tyrosine Kinase Etk
Lauren Lee, Ruiwu Liu, Nianhuan Yao, Jan Marik, Ching-Yi Hsieh, Hsing-Jien Kung, Kit Lam
180. Identification of High Affinity Anti-MCP-1 Antibodies using Synthetic Proteins
Marian Kruszynski, Ping Tsui, Jinquan Luo, Anuk Das1, Nicole Stowell, Michael Brigham-Burke, Jennifer F. Nemeth, Li Yan, Heena Beck, Jil Carton, Raymond Sweet, George A. Heavner, Michael Bardroff, Daniela D. Ducata, Ute Jager, Robert Rauchenberger
181. Mapping Cell Binding using Collagen III “Toolkit”
Nicolas F. Raynal, Tony Peachey, Richard W. Farndale
182. Modeling of a
Slavica Eri, Tomaž Šolmajer, Marko Oblak, Miha Kotnik, Danica Agbaba
183. Characterization of the Interaction of HIP Analog Peptide with Heparin
Jing Wang, Dallas Rabenstein
184. New Urotensin-II Analogs Modified at Position 4
Paolo Grieco, Pietro Campiglia, Alfonso Carotenuto, Teresa Lama, Ettore Novellino, Paolo Rovero, Guido Iaccariono
185. New Urotensin-II Analogs with a Constrained Trp-7 Side Chain
Alfonso Carotenuto, Paolo Grieco, Pietro Campiglia, Teresa Lama, Ettore Novellino, Paolo Rovero, Guido Iaccarino
186. Novel GnRH Antagonists Derived from Degarelix: Exploration of the GnRH Antagonist Pharmacophore
Manoj P. Samant, Doley J. Hong, Glenn Croston, Catherine Rivier, Jean Rivier
187. Novel Neuroprotective Neurotrophic NAP Analogs Targeting Iron Toxicity and Oxidative Stress in Neurodegenerative Diseases
Hailin Zheng, Dan Blat, Moussa B. H. Youdim, Lev M. Weiner, Dudy Dangoor, Ilana Gozes, Mati Fridkin
188. One-bead One-compound: Different Type of Screening Assays for Anti-bacterial Adhesion
Yanlei Liu, Li Peng, Xiaobing Wang, Kit S. Lam, Joseph W. Leung
189. Peptide - Mediated Delivery of siRNA via Noncovalent Complexes and Covalent Conjugates
Renata T. Witkowska, Mohammad Ahmadian, James W. Dattilo, Lafe J. Purvis, Sasha J. Mayer, Lishan Chen, Yuching Chen, Kunyuan Cui, Ken W. Farber, Sharin E. Roth, Michael E. Houston, Paul H. Johnson, Steven C. Quay
190. Peptides Reproducing the ApoA-I 141–164 Region: Studies on Hpt Recognition
Luca D. D’Andrea, MariaStefania Spagnuolo, Angela Stefano, Marianna Morra, Alessandro Carlucci, Annarita Gatto, Pasqualina Caso, Carlo Pedone, Paolo Abrescia, Ettore Benedetti
191. Peptidomimetic Inhibitors of Platelet Adhesion as Potential Novel Antiplatelet Agents
Vivienne Buckley, Elise Bernard, Edelmiro Moman, Lorraine Coleman, Dermot Kenny, Marc Devocelle
192. Peptidyl-based Delivery Systems as a Strategy for the Therapeutic Intervention of Human Astrocytoma and Medulloblastoma
Sarah Jones, John Howl
193. Photolabeling with N-Terminal Urotensin II Photoprobes Identifies Methionine 288 of Rat Urotensin Receptor as a Contact Point
Brian J. Holleran, Christophe Proulx, Marie-Ève Beaulieu, Emanuel Escher, Richard Leduc
194. Protein Kinase C Isoform (PKC) Peptide Activator/Inhibitors Exert Cardioprotective Effects in Polymorphonuclear Leukocyte (PMN)-induced Ischemia/Reperfusion (I/R) Injury
Lindon H. Young, Aisha Phillipson, Didi Omiyi, Norrell Atkinson, Manoj Jivani, Jovan Adams, Ellen E Peterman, Philip Taormina, Richard J. Brue, Margaret Harvey
195. Rational Design of Small Molecules for a Novel Class of Anti-Cancer Drugs using a Phenylalanine Library
Lajos Gera, Daniel C. Chan, Laimute Taraseviciene-Stewart, Vitalija Simkeviciene, Paul A. Bunn, John M. Stewart
196. Repair of Photodamaging Effects on Human Melanocytes by 4-Phenylbutryl-His-
James J. Knittel, Leonid N. Koikov, Pilgrim Jackson, Glenn Milhauser, Ana Luisa Kadekaro, Renny J. Kavanagh, Zalfa Abdel-Malek
197. RGD Peptide-Labeled Quantum Dots for Integrin a
Weibo Cai, Xianzhong Zhang, Yun Wu, Xiaoyuan Chen
198. Rigid Cyclic Tetrapeptides as Probes and Mimics of Reverse Turns
Sage Berg-Cross, Garland Marshall
199. Solid-Phase Synthesis and Structure Characterization of
Nian-Huan Yao, James R. Carlson, Gang Liu, Kit S. Lam
200. Stereo-controlled Synthesis of [
Hirokazu Tamamura, Kenichi Hiramatsu, Satoshi Ueda, Zixuan Wang, John O. Trent, Stephen C. Peiper, Naoki Yamamoto, Hideki Nakashima, Akira Otaka, Nobutaka Fujii
201. Stochiometric Inhibition of ß-Amyloid Fibrillogenesis using C
Marcus A. Etienne, Cyrus Bett, Jed P. Aucoin, Tim J. Jensen, Robin L. McCarley, Ted Ajmo, Donna Herber, David Morgan, Robert P. Hammer
202. Structure Determination of the Human Angiotensin II Receptor Type 1 by the Methionine Proximity Assay
Martin Clément, Stéphane S. Martin, Caroline Chamberland, Marie-Ève Beaulieu, Richard Leduc, Gaétan Guillemette, Emanuel Escher
203. Structure-Activity Relationship Studies of a Novel CXCR4 Chemokine Antagonist Reveal Unique Activity Profile
Celia Amela-Cortés, Martha Rezende, Tatyana Yakovleva, Dan Papa, Elisabeth Perchellet, Jean-Pierre Perchellet, Sandra C. Vigil-Cruz
204. Studies on a Mutual Prodrug of Sulfamethoxazole and Nalidixic acid
Asif Husain, M. S. Y. Khan
205. Studies on Interaction of CaM with CaM-Binding Peptides M13 and RS20 in the Presence of Al
Andrea Calderan, Paolo Ruzza, Alessio Osler, Andrea Guiotto, Barbara Biondi, Gianfranco Borin
206. Studies on the Peroxidase Mimetic Peptide
Liping Wang, Xiaoming Zhao, Lili Guo, Roger W. Roeske, Wei Li
207. Use of Combinatorial Peptide Libraries and LC/MS/MS to Study TPP I Substrate Specificity
Yu Tian, Istvan Sohar, John W. Taylor, Peter Lobel
208. Sunflower Derived Trypsin Inhibitors as Anti-Metastatics
Peter P. Roller, Sheng Jiang, Peng Li, Ya-Qiu Long, Sheau-Ling Lee, Cheng-Yong Lin, Michael Johnson, Richard B. Dickson
209. Surface Plasmon Resonance- and Quartz Crystal Microbalance-based Methods for Detecting GRB2 SH2 / Peptide Interaction
Feng-Di T. Lung, Wan Ching Li, Chien-Chung Liou
210. Synthesis and Biological Activity of Terlipressin and its Putative Metabolites
Kazimierz Wisniewski, Sudar Alagarsamy, Hiroe Taki, Marcel Miampamba, Regent Laporte, Robert Galyean, Glenn Croston, Claudio Schteingart, Pierre Riviere, Jerzy Trojnar
211. Synthesis and Evaluation of Neuroprotective
Andrea Guiotto, Andrea Calderan, Paolo Ruzza, Alessio Osler, Chiara Rubini, Dong-Gyu Jo, Sung-Chun Tang, Thiruma V. Arumugam, Mark P. Mattson, Gianfranco Borin
212. Synthesis, Structural Characterization and Reactivity Study of Humanin, an Alzheimer’s Disease Associated Peptide
Madalina Maftei, Heiko Moeller, Xiaodan Tian
213. Synthesis of 4-amino-1,2,4,5-tetrahydro-2-benzazepine-3-ones and Study of their ß-turn Inducing Properties
Isabelle Eynde, Karolien Rompaey, Steven Ballet, Rien Wachter, Kenno Vanommeslaeghe, Monique Biesemans, Rudolph Willem, Dirk Tourwé
214. Synthesis of a RGD Peptide-PEG Hybrid for Carrying Adenovirus Vector into Cells
Shinya Kida, Mitsuko Maeda, Keiko Hojo, Yusuke Eto, Jian-Qing Gao, Shinnosuke Kurachi, Fumiko Sekiguchi, Hiroyuki Mizuguchi, Takao Hayakawa, Tadanori Mayumi, Shinsaku Nakagawa, Koichi Kawasaki
215. Synthesis of Cyclic Imino Acids from a-Amino-?-Bromoalkanoic Acids
Louis A. Watanabe, Mohammed P. I. Bhuiyan, Tamaki Kato, Norikazu Nishino
216. Synthesis of Quantum Dots Labeled Short Peptides and their Application in Imaging the T Cell Surface Receptors
Lifeng Wang, Jie Chen, Liping Wang, Chunlei Wang, Wei Li
217. Synthesis of Quantum Dot-Signal Peptides Bioconjugates and Targeting in Living Cells
Yaming Shan, Jiayue Hu, Liping Wang, Wei Li
218. Synthesis of Symmetrical Dimeric Dicarboxylic Acid Linked Peptides on Solid Support
Sheng Jiang, Zaneta Nikolovska-Coleska, Shaomeng Wang, Peter P. Roller
219. Systematic Study on the Structure-Activity Relationship of Pyrazinone Ring-Containing Bioactive Opioid Ligands
Kimitaka Shiotani, Anna Miyazaki, Tingyou Li, Yuko Tsuda, Toshio Yokoi, Akihiro Ambo, Yusuke Sasaki, Yunden Jinsmaa, Sharon D. Bryant, Lawrence H. Lazarus, Yoshio Okada
220. Tetra and Pentapeptide Derivatives of Hemiasterlin. Synthesis and Activity Studies
Marcin Dyba, Nadya I. Tarasova, Teresa Kosakowska-Cholody, Ernest Hamel, Christopher J. Michejda
221. The Chemo-enzymatic Synthesis of Oligosaccharide-linked Peptides Aimed at Improved Drug Delivery
Ken D. Johnstone, Manuela Dieckelmann, Michael P. Jennings, Joanne T. Blanchfield, Istvan Toth
222. Neokyotorphin as Cell Protein Kinase Affector
Olga V. Sazonova, Elena Yu. Blishchenko, Anna G. Tolmazova, Dmitry P. Khachin, Andrei A. Karelin, Vadim T. Ivanov
223. Towards Inhibition of Amyloid ß-protein Oligomerization
Sean M. Spring, Summer L. Bernstein, Noel D. Lazo, Brigita Urbanc, H. Eugene Stanley, Michael T. Bowers, David B. Teplow, Gal Bitan
224. Use of Betidamino Acids in Drug Design
Judit Erchegyi, Sandra Wenger, Beatrice Waser, Veronique Eltschinger, Renzo Cescato, Jean Claude Reubi, Steven C. Koerber, Christy R. R. Grace, Roland Riek, Jean E. Rivier
225. Helical Peptide Analogs of gp41 to Develop an HIV Vaccine
Florence M. Brunel, Michael B. Zwick, Ian A. Wilson, Dennis R. Burton, Philip E. Dawson
226. Structure-Activity Relationship Studies of a Novel AGRP-Melanocortin Chimeric Template
Krista R. Wilson, Andrzej M. Wilczynski, Joseph W. Scott, Rayna M. Bauzo, Carrie Haskell-Luevano
227. Synthesis and Pharmacological Evaluation of a New Generation of TIPP-Derived Dual-Labeled Ligands for Delta Opioid Receptors
Xin Wang, Thomas F. Murray, Jane V. Aldrich
228. Synthesis and Pharmacological Evaluation of Dual Labeled Delta Opioid Receptor Peptides
Angela M. Peck, Vivek Kumar, Thomas F. Murray, Jane V. Aldrich
229. Novel Retro-inverso Envelope Peptide Mimetic Fusion Inhibitors as a Potential Therapy for HTLV-1 Infected Individuals
Marcus P. Lynch, Sharad V. Rawale, Ahmed A. Behery, William P. Hudleson, Norihiro Takenouchi, Karen Yao, Steven Jacobson, Pravin T. P. Kaumaya
230. Heteroclitic Analogs Derived from the HTLV-1 Gag Antigen Increase Cytolytic and IFN-
Marcus P. Lynch, Jacqueline C. Lieblein, Sharad V. Rawale, Danielle M. Carbin, Pravin T. P. Kaumaya
231. Development of a Monoclonal Antibody Therapeutic for the Prevention and Treatment of
Daniel J. Kao, Robert S. Hodges
232. An Unexpected Side Reaction Involving the Deletion of an Acetylated N-Methyl-Amino Acid from the N-terminus of Peptides
Wei-Jie Fang, Marco A. Bennett, Thomas F. Murray, Jane V. Aldrich
233. Synthesis and Biological Activities of Chimeric Bioactive Peptides Based on Amino Acids Coupled to 4-Anilino-
Ravil R. Petrov, Ruben S. Vardanyan, Shou-wu Ma, Peg Davis, Yeon S. Lee, Minying Cai, Frank Porreca, Josephine Y. Lai, Victor J. Hruby
234. Discovery of Potent mMC1R Agonists with Prolonged Activity at Human Melanocytes
Aleksandar Todorovic, Jerry R. Holder, Rayna M. Bauzo, Joseph W. Scott, Renny Kavanagh, Zalfa Abdel-Malek, Carrie Haskell-Luevano
235. ß-Hairpin Minimization and Optimization
Niels H. Andersen, Katherine A. Olsen, R. Matthew Fesinmeyer, Lisa A. Eidenschink
236. Analogs of Interleukin 8 Containing non Proteinogenic Segments Show High Biological Activity
Ralf David, Annette G. Beck-Sickinger
237. Optimization of the C-terminal Sequence in Glucagon to Maximize Receptor Affinity
Jay J. Levy, Vasily M. Gelfanov, Richard D. DiMarchi
238. Design, Synthesis, and Evaluation of Piperazine-Based Small Molecule Peptide Mimetics Targeting the Melanocortin Receptors
James P. Cain, Alexander V. Mayorov, Minying Cai, Yeon-Sun Lee, Jinfa Ying, Victor J. Hruby
239. Structure-Based Design and Structure-Activity Relationships of
Cristina C. Clement, Philipp Manfred
240. A Gibberellin Mimetic Peptide Recognized by an Anti-gibberellin Monoclonal Antibody
Hikaru Hemmi, Takashi Murata, Shugo Nakamura, Kentaro Shimizu, Yoshihito Suzuki, Isomaro Yamaguchi
241. Synthesis of the Spin-labelled ß-Amino Acids
Karen Wright, Matthieu Sarciaux, Michel Wakselman, Jean-Paul Mazaleyrat, Marco Crisma, Fernando Formaggio, Cristina Peggion, Antonio Toffoletti, Carlo Corvaja, Claudio Toniolo
242. High Affinity Grb2 SH2 Domain-Binding Macrocycles Derived from Ring-Closing Methathesis of Alkenylglyicne Residues with ß-Vinyl Phosphotyrosyl Mimetics
Fa Liu, Shinya Oishi, Rajeshri Karki, Zhen-Dan Shi, Karen M. Worthy, Lakshman K. Bindu, Melissa Maderia, Marc Nicklaus, Joseph J. Barchi, Robert J. Fisher, Terrence R. Burke
243. Towards Photo-Controlled Collagens
Ulrike Kusebauch, Sergio A. Cadamuro, Luis Moroder, Christian Renner
244. Template-Assembled Peptide Models of the N-Peptide Helix Bundle from HIV-1 gp41
Weiming Xu, John W. Taylor
245. Alignment of Three Nitroxide Radicals on the Same Face of a Helical Peptide Scaffold
Marco Crisma, Simona Oancea, Fernando Formaggio, Elena Sartori, Carlo Corvaja, Claudio Toniolo
246. Design, Synthesis, and Preferred Conformation of Peptides Based on a Highly Constrained, ß,ß'-Diphenyl Substituted Cyclopropane a-Amino Acid
Soledad Royo, Wim M. Borggraeve, Cristina Peggion, Marco Crisma, Ana I. Jiménez, Carlos Cativiela, Claudio Toniolo
247. Identification of a Novel HIV-1 Neutralizing Antibody Using Synthetic Peptides that Mimic a GP41 Fusion Intermediate
Elisabetta Bianchi, Michael D. Miller, Romas Geleziunas, Gaetano Barbato, Paolo Ingallinella, Marco Finotto, Renee Hrin, Meiqing Lu, Simon Lennard, David Lowe, Gennaro Ciliberto, Daria Hazuda, Riccardo Cortese, John Shiver, Antonello Pessi
248. Covalent Trimeric Coiled Coils of the HIV gp41 HR1 Region are Extremely Potent and Broadly Neutralizing Inhibitors of Viral Infection
Elisabetta Bianchi, Marco Finotto, Paolo Ingalinella, Renee Hrin, Michael D. Miller, Romas Geleziunas, Antonello Pessi
249. Selective Agonists for the Human Vasopressin V
Stoytcho B. Stoev, LingLing Cheng, Maurice Manning, Nga C. Wo, Hazel H. Szeto, Ana Pena, Brigitte Murat, Sylvain Derick, Miguel Trueba, Maria A. Ventura, Gilles Guillon
250. Prion Protein Misfolding: Conformational Stability of the a2-Helix
Pasqule Palladino, Luisa Ronga, Barbara Tizzano, Filomena Rossi, Raffaele Ragone, Teodorico Tancredi, Gabriella Saviano, Angelo Facchiano, Susan Costantini, Menotti Ruvo, Ettore Benedetti
251. Modeling Flexible Loops in the Dark-Adapted and Activated States of Rhodopsin, a Prototypical G-protein-Coupled Receptor
Gregory V. Nikiforovich, Garland R. Marshall
252. Deducing 3D Models of the Activated States for TM Regions of GPCRs by Modeling Constitutively Active Mutants: The Test Case of Opsin
Gregory V. Nikiforovich, Garland R. Marshall
253. Identification of a Unique Stability Propagation Site that Controls Protein Stability of a-Tropomyosin: a Two-Stranded a-Helical Coiled-coil
Janine B. Mills, Stanley C. Kwok, Lawrence B. Smillie, Robert S. Hodges
254. The Introduction of Uncharged a-Hydroxymethyl Amino Acid Residues in Substrate Specificity P
Ewa Zablotna, Agnieszka Kret, Anna Jaskiewicz, Aleksandra Olma, Miroslaw T. Leplawy, Krzysztof Rolka
255. Molecular Simulation of an a/?-Peptide Dendrimer
Qitao Yu, Yuguang Mu, Lars Nordenskiold, James P. Tam
256. A GHS-1a Receptor Agonist that is Highly Effective in Stimulating Body Weight Gain
Jesse Z. Dong, John Eynon, Jundong Zhang, John E. Taylor, Heather A. Halem, Rakesh Datta, Michael D. Culler
257. A Non-Competitive Peptide Agonist of GHSR1a Receptor Stimulates Growth Hormone Secretion and Food Intake
Abdelkrim Habi, Patric Delhanty, Daniel Abran, Aart Jan Lely, Krishna G. Peri
258. Development of µ Opioid Receptor Selective 4-Anilinidopiperidine Analogs
Yeon Sun Lee, Joel Nyberg, Sharif Moye, Richard Agnes, Adriano Mollica, Peg Davis, Shou-Wu Ma, Josephin Lai, Frank Porreca, Ruben Vardanyan, Victor J. Hruby
259. A Whole-Cell Binding Assay for Testing the Targeting Potential of Cyclic Peptide Ligands
Sonya Cressman, Ning Fang, David D. Y. Chen, Pieter R. Cullis
260. Synthesis and Evaluation of Chiral and Achiral a,a-Disubstituted Amino Acids as ß-Sheet Stabilizing Factors
Jia Wang, Robert P. Hammer
261. Evaluation of Malarial Protease Plasmepsin Inhibitors Containing Hydroxymethylcarbonyl Isostere
Koushi Hidaka, Tooru Kimura, Yumi Tsuchiya, Aiko Kiso, Yoshio Hayashi, Azin Nezami, Ernesto Freire, Yoshiaki Kiso
262. Design and Synthesis of
Yoshio Hamada, Daisuke Shuto, Naoto Igawa, Soko Kasai, Ping Liu, Koushi Hidaka, Tooru Kimura, Yoshio Hayashi, Shoichi Ishiura, Yoshiaki Kiso
263. Synthesis of Non-linear Potential Vaccines for HSV-1
Rosalba Mansi, Stefania Galdiero, Diego Tesauro, Ettore Benedetti, Giancarlo Morelli, Massiliano Galdiero
264. Intramolecular Triplet Quenching by Nitroxide Radicals as a Tool for Determining Peptide Secondary Structure in Solution
Lorenzo Stella, Gianfranco Bocchinfuso, Emanuela Gatto, Antonio Palleschi, Mariano Venanzi, Daniela Zavallone, Andrea Bettio, Fernando Formaggio, Claudio Toniolo, Basilio Pispisa
265. A Time-Resolved Spectroscopic Study on Peptide Folding
Basilio Pispisa, Emanuela Gatto, Gianfranco Bocchinfuso, Antonio Palleschi, Lorenzo Stella, Mariano Venanzi, Fernando Formaggio, Claudio Toniolo
266. Ion Channel Activities and Mechanisms of Ion Conduction about Cyclic Hexapeptides
Junichi Taira, Ryo Hayashi, Satoshi Osada, Tsuguhisa Ehara, Hiroaki Kodama
267. Synthesis and Biological Activities of Proline Rich Cyclic Heptapeptide Hymemanide B Analogs
Yasuhiro Shiki, Junichi Taira, Aya Nakamura, Satoshi Osada, Hiroaki Kodama
268. Synthesis and Biomaterials Application of Polymers Containing Pentapeptide and/or Hexapeptide Sequences Derived from Elastin
Kouji Okamoto, Shuichiroh Uehara, Kayoko Matsui, Maria Portia P. Briones, Iori Maeda, Masakazu Furuta
269. Synthesis and Biological Activities of fMLP Analogs Containing 2,3-Cyclopropane Amino Acid Derivatives
Daisuke Sugiyama, Ryo Hayashi, Hiroshi Kawasaki, Hiroaki Kodama, Satoshi Osada, Masafumi Zaitsu, Ichiro Fujita
270.
Wayne D. Kohn, Radmila Micanovic, Sharon L. Myers, Andrew M. Vick, Steven Kahl, Lianshan Zhang, Beth Strifler, Shun Li, Jing Shang, John M. Beals, John P. Mayer, Richard D. DiMarchi
271. N-Backbone Methylations of Parathyroid Hormone (PTH) C-Terminal Region: Bioactivities and Implications for PTH-Receptor Complex
Zhanna Potetinova, Jean-René Barbier, Thomas J. Gardella, Thomas Dean, James F. Whitfield, Gordon E. Willick
272. N-Backbone Methylations of Parathyroid Hormone (PTH) C-Terminal Region: Effects on Structure
Zhanna Potetinova, Feng Ni, Gordon E. Willick
273. C-Terminal Modified Parathyroid Hormone: Effects on Structure and Activity
Zhanna Potetinova, Jean-Rene Barbier, Thomas Dean, Thomas J. Gardella, Gordon E. Willick
274. Spectroscopic Characterization of PEG-Amylin Derivatives
Giuseppe Impellizzeri, Diego Mendola, Antonio Magrì, Giuseppe Maccarrone, Giuseppe Pappalardo, Enrico Rizzarelli
275. Conformational Properties and Functional Role of VDAC N-Terminal Peptide
Vito Pinto, Angela Messina, Rita Aiello, Flora Tomasello, Diego Mendola, Antonio Magrì, Danilo Milardi, Giuseppe Pappalardo
276. Design of Membrane Active Peptides with Regularly Repeating Glycine or
Jyothi Thundimadathil, Roger W. Roeske, Lili Guo
277. Design and Synthesis of Novel a-MSH Peptide Analogs Highly Selective for the hMC4R
Victor J. Hruby, Jinfa Ying, Xuyuan Gu, Minying Cai, Josef Vagner, Dev B. Trivedi, Katalin E. Kövér
278. Design, Synthesis and Characterization of Conformational Peptides at the Interface of HER-2 Dimerization and Pertuzumab Binding
Joan T. Steele, Sharad Rawale, Pravin T. P. Kaumaya
279. Synthesis of a Phosphino Triple Helical Collagen Mimic
John K. Whitehead, Shunzi Li, LaKeisha N. Myles, Robert P. Hammer, Gregg B. Fields
280. Steric Hindrance of the HER-2/neu Dimerization Loop by Peptide Mimic Antibodies
Stephanie D. Allen, Sharad Rawale, Pravin T. P. Kaumaya
281. Hydrogen/Deuterium Exchange Studies on Helical Peptides in a DMSO/MeOD Solvent System
Erin Daly, Adam Blom, Matt Kubasik
282. Octapeptide Analogs of Somatostatin Containing a,a-Dialkylated Amino Acids with Potent Anticancer Activity
Sudhanand Prasad, Archna Mathur, Neena Gupta, Manu Jaggi, Anu T. Singh, Rama Mukherjee
283. Backbone Cyclization Improves the Enzymatic Stability of ?-Conotoxin, MrIA, whilst Maintaining its Structure and NET-Modulating Activity
Erica S. Lovelace, Christopher J. Armishaw, Michelle L. Colgrave, Paul F. Alewood, Norelle L. Daly, David J. Craik
284.
Soumendra Rana, Bijoy Kundu, Susheel Durani
285. Restructuring Artificial Peptide Networks by External Triggering
Gonen Ashkenasy, M. Reza Ghadiri
286. Development of a Stilbene-type Photoswitchable ß-Hairpin Mimetic
Máté Erdélyi, Adolf Gogoll
287. The Guanidinium Group: A Key Player in Molecular Recognition
Ernest Giralt, Susana Gordo, Ignasi Belda, Silvia Pujals, Marc Martinell, Xavier Salvatella, Jimena Fernández-Carneado
288. Novel and Highly Selective Antagonist Scaffold for Human Melanocortin 3 Receptor: Computer-Aided Design and Biological Evaluation
Alexander V. Mayorov, Minying Cai, Kevin B. Chandler, Ravil R. Petrov, April R. Scoy, Zerui Yu, Dustin K. Tanaka, Dev Trivedi, Victor J. Hruby
289. Transmembrane Peptide Segments of the Uncoupling Protein-1: Chemical Synthesis and Biophysical Properties
Masoud Jelokhani-Niaraki, Marina Ivanova
290. Discovery and Optimization of ß-MSH Derived Melanocortin-4 Selective Agonists
John P. Mayer, Hansen M. Hsiung, David B. Flora, Patrick Edwards, Dennis P. Smith, Xing-Yue Zhang, Robert A. Gadski, Mark L. Heiman, JeAnne L. Hertel, Paul J. Emmerson, Saba Husain, Thomas P. O’Brien, Steven D. Kahl, David L. Smiley, Lianshan Zhang, Richard D. DiMarchi, Liang Zeng Yan
291. Molecular Mechanisms of Constitutive Activity: Mutations at Position 111 of the Angiotensin AT
Gregory V. Nikiforovich, Balász Mihalik, Kevin J. Catt, Garland R. Marshall
292. A Surprise End to 20 Year Search for Selective Agonists for Rat Vasopressin V
Maurice Manning, LingLing Cheng, Stoytcho B. Stoev, Nga C. Wo, Hazel H. Szeto, Ana Pena, Brigitte Murat, Miguel Trueba, Maria A. Ventura, Gilles Guillon
293. Furanoid Sugar Amino Acids in Design of Analogs of VIP Receptor Binding Inhibitor
Sudhanand Prasad, Archna Mathur, Manu Jaggi, Rajan Sharma, Neena Gupta, Rama Mukherjee, Ajit C. Kunwar, Tushar K. Chakraborty
294. Two Residues at the Extracellular Face of TM5 and TM6 Interact in the Active State of a G Protein-coupled Receptor
Yong-Hun Lee, Fred Naider, Jeffrey M. Becker
295. Molecular Probes for Visualizing Angiogenesis
Alan Cuthbertson, Grete Mørk Kindberg, Bård Indrevoll, Joseph Arukwe, Hege Karlsen, Alex Gibson, Julie Davis, Marivi Mendizabal, Matthew Morrison, Matthias Glaser
296. The Two Cysteine-rich Head Domains of Minicollagen from
Alexander G. Milb
Keywords: SCIENCE / Life Sciences / Biology / General SCI008000
- Author(s)
- Blondelle, Sylvie E.
- Publisher
- Springer
- Publication year
- 2006
- Language
- en
- Edition
- 1
- Category
- Natural Sciences
- Format
- Ebook
- eISBN (PDF)
- 9780387265759