Metabolome Analyses: Strategies for Systems Biology

1. Introduction
Seetharaman Vaidyanathan, George G. Harrigan, Royston Goodacre

2. Towards Integrative Functional Genomics Using Yeast as a Reference Model
Juan I. Castrillo, Stephen G. Oliver

3. Metabolomics for the Assessment of Functional Diversity and Quality Traits in Plants
Robert D. Hall, C.H.Ric Vos, Harrie A. Verhoeven, Raoul J. Bino

4. Metabolomics: A New Approach Towards Identifying Biomarkers and Therapeutic Targets in CNS Disorders
Rima Kaddurah-Daouk, Bruce S. Kristal, Mikhail Bogdanov, Wayne R. Matson, M. Flint Beal

5. Comparative Metabolome Profiling Using Two Dimensional Thin Layer Chromatography (2DTLC)
Thomas Ferenci, Ram Maharjan

6. Capillary Electrophoresis and Its Application in Metabolome Analysis
Li Jia, Shigeru Terabe

7. Metabolite Profiling with GC-MS and LC-MS
Ralf Looser, Amo J. Krotzky, Richard N. Trethewey

8. The Application of Electrochemistry to Metabolic Profiling
David F. Meyer, Paul H. Gamache, Ian N. Acworth

9. Differential Metabolic Profiling for Biomarker Discovery
Haihong Zhou, Aaron B. Kantor, Christopher H. Becker

10. NMR-Based Metabonomics in Toxicology Research
Laura K. Schnackenberg, Richard D. Beger, Yvonne P. Dragan

11. Methodological Issues and Experimental Design Considerations in Metabolic Profile-Based Classifications
Bruce S. Kristal, Yevgeniya Shurubor, Ugo Paolucci, Wayne R. Matson

12. Modelling of Fungal Metabolism
Helga David, Jens Nielsen

13. Detailed Kinetic Models Using Metabolomics Data Sets
Jacky L. Snoep, Johann M. Rohwer

14. Metabolic Networks
Eivind Almaas, Zoltán N. Oltvai, Albert-László Barabási

15. Metabolic Networks from a Systems Perspective
Wolfram Weckwerth, Ralf Steuer

16. Parallel Metabolite and Transcript Profiling
Alisdair R. Fernie, Ewa Urbanczyk-Wochniak, Lothar Willmitzer

17. Fluxome Profiling in Microbes
Nicola Zamboni, Uwe Sauer

18. Targeted Drug Design and Metabolic Pathway Flux
László G. Boros, Wai-Nang Paul Lee

19. Metabonomics in the Pharmaceutical Industry
Eva M. Lenz, Rebecca Williams, Ian D. Wilson

20. How Lipidomic Approaches Will Benefit the Pharmaceutical Industry
Alvin Berger

21. Metabolites and Fungal Virulence
Edward M. Driggers, Axel A. Brakhage

Keywords: Life Sciences, Bioinformatics, Internal Medicine, Analytical Chemistry, Biochemistry, general