Proteomics and Protein-Protein Interactions

1. Introduction: Proteomics and Protein-Protein Interactions: Biology, Chemistry, Bioinformatics, and Drug Design
Gabriel Waksman, Clare Sansom

2. Yeast Two-Hybrid Protein-Protein Interaction Networks
Daniel Auerbach, Igor Stagljar

3. The Use of Mass Spectrometry in Studying Protein-Protein Interaction
Yi Wang, Parvin Yazdi, Jun Qin

4. Molecular Recognition in the Immune System
Eric J. Sundberg, Roy A. Mariuzza

5. Computational Methods for Predicting Protein-Protein Interactions
A. Walker-Taylor, D. T. Jones

6. Protein-Protein Docking Methods
Garland R. Marshall, Ilya A. Vakser

7. Thermochemistry of Binary and Ternary Protein Interactions Measured by Titration Calorimetry: Complex Formation of CD4, HIV gp120, and Anti-gp120
Michael L. Doyle, Preston Hensley

8. Protein-Protein Recognition in Phosphotyrosine-Mediated Intracellular Signaling
John E. Ladbury

9. Competitive Binding of Proline-Rich Sequences by SH3, WW, and Other Functionally Related Protein Domains
Marius Sudol, Mark T. Bedford

10. The Structure and Molecular Interactions of the Bromodomain
Kelley S. Yan, Ming-Ming Zhou

11. SMART Drug Design: Novel Phosphopeptide and ATP Mimetic-Based Small Molecule Inhibitors of the Oncogenic Protein Kinase pp60src (Src)
T. K. Sawyer, R. S. Bohacek, W. C. Shakespeare, C. A. Metcalf, Y. Wang, R. Sundaramoorthi, T. Keenan, S. Narula, D. C. Dalgarno

12. Disrupting Protein-Protein Interaction: Therapeutic Tools Against Brain Damage
Michelle Aarts, Michael Tymianski

13. A Thermodynamic Guide to Affinity Optimization of Drug Candidates
Ernesto Freire

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Keywords: SCIENCE / Life Sciences / Biology / General SCI008000