Brown, David R.

Neurodegeneration and Prion Disease

Brown, David R. - Neurodegeneration and Prion Disease, ebook


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ISBN: 9780387239231
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Table of contents

1. Introduction
David R. Brown

2. Neuropathology of Transmissible Spongiform Encephalopathies (Prion Diseases)
Pawel P. Liberski, James W. Ironside

3. Central Pathogenesis of Prion Diseases
Ursula Unterberger, Till Voigtländer, Herbert Budka

4. Hereditary Prion Protein Amyloidoses
Bernardino Ghetti, Pedro Piccardo, Orso Bugiani, Gianluigi Forloni, Michela Morbin, Mario Salmona, Fabrizio Tagliavini

5. Mouse Behavioural Studies and What They Can Teach Us about Prion Diseases
Colm Cunningham

6. Electrophysiological Approaches to the Study of Prion Diseases
Nikki K. MacLeod, Alex R. Johnston, John C. Curtis

7. Prion Protein, Prion Protein-Like Protein, and Neurodegeneration
Suehiro Sakaguchi

8. Oxidative Stress and Mitochondrial Dysfunction in Neurodegeneration of Transmissible Spongiform Encephalopathies (TSEs)
Boe-Hyun Kim, Jae-II Kim, Richard I. Carp, Yong-Sun Kim

9. Mechanisms of Prion Toxicity and Their Relationship to Prion Infectivity
Laura Vella, Andrew F. Hill, Roberto Cappai

10. A Stone Guest on the Brain: Death as a Prion
David R. Brown

11. Molecular Mechanisms Mediating Neuronal Cell Death in Experimental Models of Prion Diseases, in vitro
Tullio Florio, Stefano Thellung, Gennaro Schettini

12. Processing and Mis-Processing of the Prion Protein: Insights into the Pathogenesis of Familial Prion Disorders
Neena Singh, Yaping Gu, Sharmila Bose, Subhabrata Basu, Xiu Luo, Richa Mishra, Oscar Kuruvilla

13. Signaling Pathways Controling Prion Neurotoxicity: Role of Endoplasmic Reticulum Stress-Mediated Apoptosis
Rodrigo Morales, Claudio Hetz, Claudio Soto

14. Cell Culture Models to Unravel Prion Protein Function and Aberrancies in TSE
Katarina Bedecs

15. Insights into the Cellular Trafficking of Prion Proteins
Max Nunziante, Sabine Gilch, Hermann M. Schätzl

16. The Molecular Basis of Prion Protein-Mediated Neuronal Damage
Ramanujan S. Hegde, Neena S. Rane

17. Conclusion: Intervention, the Final Frontier
David R. Brown


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Keywords: TECHNOLOGY & ENGINEERING / Biomedical TEC059000

Publication year
Medicine, Health Care, Mode

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