Harris, J. Robin

Alzheimer’s Disease

Alzheimer’s Disease


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ISBN: 9780387232263
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Table of contents

1. The Contribution of Microscopy to the Study of Alzheimer’s Disease, Amyloid Plaques and Aß Fibrillogenesis
J. Robin Harris

2. Transgenic Mouse Models for APP Processing and Alzheimer’s Disease: Early and Late Defects
Tom Dooren, Ilse Dewachter, Peter Borghgraef, Fred Leuven

3. Oxidative stress in Alzheimer’s Disease: Implications for Prevention and Therapy
Christian Behl

4. ß-Secretase, APP and Aß in Alzheimer’s Disease
Robert Vassar

5. The Non-Amyloidogenic Pathway: Structure and Function of a-Secretases
Elzbieta Kojro, Falk Fahrenholz

6. Amyloid ß Degradation: A Challenging Task for Brain Peptidases
Laura Morelli, Ayelén Bulloj, María Celeste Leal, Eduardo M. Castaño

7. The Protective Role of Vitamin E in Vascular Amyloid ß-Mediated Damage
Francisco José Muñoz, Montserrat Solé, Mireia Coma

8. Amyloid Accumulation and Pathogensis of Alzheimer’s Disease: Significance of Monomeric, Oligomeric and Fibrillar Aß
Charles C. Glabe

9. Cholesterol and Amyloid ß Fibrillogenesis
Katsuhiko Yanagisawa

10. Alzheimer’s ß-Amyloid: Insights into Fibril Formation and Structure from Congo Red Binding
Hideyo Inouye, Daniel A. Kirschner

11. The Aluminium-Amyloid Cascade Hypothesis and Alzheimer’s Disease
Christopher Exley

12. Amyloid-ß Metal Interaction and Metal Chelation
Math P. Cuajungco, Christopher J. Frederickson, Ashley I. Bush

13. The Interaction of Amyloid-ß with ApoE
Donald B. Carter

14. Clusterin and Alzheimer’s Disease
Miguel Calero, Agueda Rostagno, Blas Frangione, Jorge Ghiso

15. Acetylcholinesterase Interaction with Alzheimer Amyloid ß
Nibaldo C. Inestrosa, Juan Paulo Sagal, Marcela Colombres

16. Membrane Disordering Effects of ß-Amyloid Peptides
Gunter P. Eckert, W. G. Wood, W. E. Müller

17. The Role of Alzheimer Aß Peptides in Ion Transport Across Cell Membranes
Vernon M. Ingram

18. Amyloid Inhibitors and ß-Sheet Breakers
Claudio Soto, Lisbell Estrada

19. Cholesterol and Alzheimer’s Disease: Statins, Cholesterol Depletion in APP Processing and Aß Generation
Tobias Hartman

20. Phosphorylated Amyloid-ß: the Toxic Intermediate in Alzheimer’s Disease Neurodegeneration
Nathaniel G. N. Milton


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Keywords: SCIENCE / Life Sciences / Biology / General SCI008000

Publication year
Natural Sciences

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