Multichain Immune Recognition Receptor Signaling

Section I.. MIRRs: Structure and Physiological Function

1. T-Cell Receptor
Jose M. Rojo, Raquel Bello, Pilar Portolés

2. B-Cell Receptor
Randall J. Brezski, John G. Monroe

3. Fc Receptors
Maree S. Powell, P. Mark Hogarth

4. Natural Killer Cell Receptors
Roberto Biassoni

5. Platelet Glycoprotein VI
Stephanie M. Jung, Masaaki Moroi

Section II.. MIRR Signaling: Possible Mechanisms and the Techniques to Study and Visualize

6. Clustering Models
Wolfgang W.A. Schamel, Michael Reth

7. Segregation Models
Elaine P. Dopfer, Mahima Swamy, Gabrielle M. Siegers, Eszter Molnar, Jianying Yang, Wolfgang W. A. Schamel

8. Kinetic Proofreading Model
Byron Goldstein, Daniel Coombs, James R. Faeder, William S. Hlavacek

9. Serial Triggering Model
Jacob Rachmilewitz

10. Conformational Model
Ruth M. Risueño, Angel R. Ortiz, Balbino Alarcón

11. Permissive Geometry Model
Susana Minguet, Wolfgang W.A. Schamel

12. Signaling Chain Homooligomerization (SCHOOL) Model
Alexander B. Sigalov

13. Visualization of Cell-Cell Interaction Contacts-Synapses and Kinapses
Michael L. Dustin

14. Visualization of Protein Interactions in Living Cells
Tomasz Zal

Section III.. MIRR Signaling and Therapy of Immune Disorders

15. Immunogenicity in Peptide-Immunotherapy: From Self/Nonself to Similar/Dissimilar Sequences
Darja Kanduc

16. Therapeutic Application of Transmembrane T and Natural Killer Cell Receptor Peptides
Nicholas Manolios, Marina Ali, Michael Amon, Veronika Bender

17. Fc Receptor Targeting in the Treatment of Allergy, Autoimmune Diseases and Cancer
Akira Nakamura, Tomohiro Kubo, Toshiyuki Takai

18. Therapeutic Blockade of T- Cell Antigen Receptor Signal Transduction and Costimulation in Autoimmune Disease
Joseph R. Podojil, Danielle M. Turley, Stephen D. Miller

19. MHC and MHC-Like Molecules: Structural Perspectives on the Design of Molecular Vaccines
Vasso Apostolopoulos, Eliada Lazoura, Minmin Yu

20. SCHOOL Model and New Targeting Strategies
Alexander B. Sigalov

21. Immune Receptor Signaling, Aging and Autoimmunity
Anis Larbi, Tamas Fülöp, Graham Pawelec

22. Viral Pathogenesis, Modulation of Immune Receptor Signaling and Treatment
Walter M. Kim, Alexander B. Sigalov

Keywords: Biomedicine, Biomedicine general