, PhD, Charles E. Ribak
From Development to Degeneration and Regeneration of the Nervous System
The second section on degenerative disorders of the brain begins wtih details about the dopaminergic neurons in the substantia niger and their loss in Parkinson's disease. Two subsequent chapters describe changes in brain aging, including changes in the numbers of myelinated axons. Other chapters in this section describe important cellular and molecular changes found in Alzheimer's disease and human epilepsy. Together, these chapters summarize much of our current knowledge about the major molecular and cellular changes found in several degenerative diseases of the brain.
The last section addresses the issues of brain plasticity and regeneration in the adult brain and begins with a chapter on how the brain's own stem cells provide newly generated neurons to the hippocampal dentate gyrus and how these neurons become integrated into neural circuitry. The following two chapters examine some of the neuroplastic changes that take place in motor and sensory cortices of awake behaving primates. The concluding two chapters address the issue of regeneration in the injured spinal cord and the factors that may contribute to its success.
Keywords: MEDICAL / General MED000000
- Author(s)
- , PhD, Charles E. Ribak
- , PhD, Edward G. Jones
- , PhD, Jorge A. Larriva Sahd
- , PhD, Larry W. Swanson
- , Phd, Carlos Aramburo de la Hoz
- Publisher
- Oxford University Press
- Publication year
- 2008
- Language
- en
- Edition
- 1
- Category
- Medicine, Health Care, Mode
- Format
- Ebook
- eISBN (PDF)
- 9780199709168