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RSSStatistics Applied to Clinical Trials | ||||||||||||||||||
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| Table of contents 1. Hypotheses, Data, Stratification 2. The Analysis Of Efficacy Data 3. The Analysis of Safety Data 4. Log Likelihood Ratio Tests For Safety Data Analysis 5. Equivalence Testing 6. Statistical Power And Sample Size 7. Interim Analyses 8. Controlling The Risk of False Positive Clinical Trials 9. Multiple Statistical Inferences 10. The Interpretation of The P-Values 11. Research Data Closer To Expectation Than Compatible With Random Sampling 12. Statistical Tables For Testing Data Closer To Expectation Than Compatible With Random Sampling 13. Principles Of Linear Regression 14. Subgroup Analysis Using Multiple Linear Regression: Confounding, Interaction, Synergism 15. Curvilinear Regression 16. Logistic and Cox Regression, Markow Models, Laplace Transformations 17. Regression Modeling for Improved Precision 18. Post-Hoc Analyses in Clinical Trials, a Case for Logistic Regression Analysis 19. Confounding 20. Interaction 21. Meta-Analysis, Basic Approach 22. Meta-Analysis, Review and Update of Methodologies 23. Crossover Studies with Continuous Variables 24. Crossover Studies with Binary Responses 25. Cross-Over Trials Should not be Used to Test Treatments with Different Chemical Class 26. Quality-of-Life Assessments in Clinical Trials 27. Statistical Analysis of Genetic Data 28. Relationship Among Statistical Distributions 29. Testing Clinical Trials for Randomness 30. Clinical Trials do not Use Random Samples Anymore 31. Clinical Data Where Variability is More Important than Averages 32. Testing Reproducibility 33. Validating Qualitative Diagnostic Tests 34. Uncertainty of Qualitative Diagnostic Tests 35. Meta-Analysis of Diagnostic Accuracy 36. Validating Quantitative Diagnostic Tests 37. Summary of Validation Procedures for Diagnostic Tests 38. Validating Surrogate Endpoints of Clinical Trials 39. Methods for Repeated Measures Analysis 40. Advanced Analysis of Variance, Random Effects and Mixed Effects Models 41. Monte Carlo Methods 42. Physicians’ Daily Life and the Scientific Method 43. Clinical Trials: Superiority-Testing 44. Trend-Testing 45. Odds Ratios and Multiple Regression Models, Why and How to Use Them 46. Statistics is no “Bloodless” Algebra 47. Bias Due to Conflicts of Interests, Some Guidelines | ||||||||||||||||||
| Vi levererar inte det extramaterial som ibland levereras med tryckta böcker (cd- eller dvd-skivor). | ||||||||||||||||||
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