Ehrhardt, Carsten
Drug Absorption Studies
1. Perfused Organ Level/In Situ Techniques
1. Models for Skin Absorption and Skin Toxicity Testing
Ulrich F. Schaefer, Steffi Hansen, Marc Schneider, Javiana Luengo Contreras, Claus-Michael Lehr
2. Models of the Small Intestine
Brendan Griffin, Caitriona O’Driscoll
3. Drug Absorption from the Colon In Situ
Hiroaki Yuasa
4. In Vivo and In Vitro Models for Assessing Drug Absorption Across the Buccal Mucosa
Joseph A. Nicolazzo, Barrie C. Finnin
5. In Situ and Ex Vivo Nasal Models for Preclinical Drug Development Studies
Remigius U. Agu, Michael I. Ugwoke
6. The Isolated Perfused Lung for Drug Absorption Studies
Ann Tronde, Cynthia Bosquillon, Ben Forbes
2. Cellular Level—In Vitro Models of Epithelial and Endothelial Barriers
7. In Vitro Models for Investigations of Buccal Drug Permeation and Metabolism
Tanja Obradovic, Ismael J. Hidalgo
8. In Vitro Screening Models to Assess Intestinal Drug Absorption and Metabolism
Sven Deferme, Pieter Annaert, Patrick Augustijns
9. In Vitro Cellular Models for Nasal Drug Absorption Studies
Dae-Duk Kim
10. In Vitro Models of the Tracheo-Bronchial Epithelium
Carsten Ehrhardt, Ben Forbes, Kwang-Jin Kim
11. In Vitro Models of the Alveolar Epithelial Barrier
Carsten Ehrhardt, Michael Laue, Kwang-Jin Kim
12. Cell Culture Models of the Corneal Epithelium and Reconstructed Cornea Equivalents for In Vitro Drug Absorption Studies
Stephan Reichl, Ulrich Becker
13. The Conjunctival Barrier in Ocular Drug Delivery
Hovhannes J. Gukasyan, Kwang-Jin Kim, Vincent H.L. Lee
14. Inner Blood—Retinal Barrier: Transport Biology and Methodology
Ken-ichi Hosoya, Masatoshi Tomi
15. Regulation of Paracellular Permeability in Low-Resistance Human Vaginal-Cervical Epithelia
George I. Gorodeski
16. In Vitro Models and Multidrug Resistance Mechanisms of the Placental Barrier
Pallabi Mitra, Kenneth L. Audus
17. In Vitro Models to Study Blood-Brain Barrier Function
Gert Fricker
18. High-Throughput Screening Using Caco-2 Cell and PAMPA Systems
Cheng Li, Sam Wainhaus, Annette S. Uss, Kuo-Chi Cheng
19. Instrumented In Vitro Approaches to Assess Epithelial Permeability of Drugs from Pharmaceutical Formulations
Stephan A. Motz, Michael Bur, Ulrich F. Schaefer, Claus-Michael Lehr
3. Bioinformatics—In Silico Tools to Predict Drug Absorption
20. Modeling Transdermal Absorption
Dirk Neumann
21. Physiologically Based in Silico Models for the Prediction of Oral Drug Absorption
Fredrik Johansson, Ronnie Paterson
22.
Prabha Garg, Jitender Verma, Nilanjan Roy
4. Molecular/Sub-Cellular Level—Mechanistic Tools
23. Impact of Drug Transport Proteins
Tomohiro Terada, Ken-ichi Inui
24. Cloning and Functional Heterologous Expression of Transporters
Carsten Kneuer, Walther Honscha
25. The Pharmacology of Caveolae
Stuart A. Ross, William V. Everson, Eric J. Smart
26. Immortalization Strategies for Epithelial Cells in Primary Culture
David de Semir Frappart, Rosalie Maurisse, Esther H. Vock, Dieter C. Gruenert
27. Binding-Uptake Studies and Cellular Targeting
Franz Gabor, Michael Wirth
5. Regulatory Considerations
28. Drug Permeability Studies in Regulatory Biowaiver Applications
Donna A. Volpe
DRM-restrictions
Printing: not available
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Avainsanat: TECHNOLOGY & ENGINEERING / Biomedical TEC059000
- Tekijä(t)
- Ehrhardt, Carsten
- Kim, Kwang-Jin
- Julkaisija
- Springer
- Julkaisuvuosi
- 2008
- Kieli
- en
- Painos
- 1
- Kategoria
- Terveys, kauneus, muoti
- Tiedostomuoto
- E-kirja
- eISBN (PDF)
- 9780387749013