Class 3.4–6 Hydrolases, Lyases, Isomerases, Ligases

1. aminopeptidase S 3.4.11.24
Dietmar Schomburg, Ida Schomburg

2. angiotensin-converting enzyme 2 3.4.17.23
Dietmar Schomburg, Ida Schomburg

3. SARS coronavirus main proteinase 3.4.22.69
Dietmar Schomburg, Ida Schomburg

4. sortase A 3.4.22.70
Dietmar Schomburg, Ida Schomburg

5. sortase B 3.4.22.71
Dietmar Schomburg, Ida Schomburg

6. human endogenous retrovirus K endopeptidase 3.4.23.50
Dietmar Schomburg, Ida Schomburg

7. HycI peptidase 3.4.23.51
Dietmar Schomburg, Ida Schomburg

8. ADAMTS13 endopeptidase 3.4.24.87
Dietmar Schomburg, Ida Schomburg

9. HslU-HslV peptidase 3.4.25.2
Dietmar Schomburg, Ida Schomburg

10. fatty acid amide hydrolase 3.5.1.99
Dietmar Schomburg, Ida Schomburg

11. (R)-amidase 3.5.1.100
Dietmar Schomburg, Ida Schomburg

12. L-proline amide hydrolase 3.5.1.101
Dietmar Schomburg, Ida Schomburg

13. 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5’-monophosphate deformylase 3.5.1.102
Dietmar Schomburg, Ida Schomburg

14. N-acetyl-1-d-myo-inositol-2-amino-2-deoxy-α-d-glucopyranoside deacetylase 3.5.1.103
Dietmar Schomburg, Ida Schomburg

15. peptidoglycan-N-acetylglucosamine deacetylase 3.5.1.104
Dietmar Schomburg, Ida Schomburg

16. chitin disaccharide deacetylase 3.5.1.105
Dietmar Schomburg, Ida Schomburg

17. N-formylmaleamate deformylase 3.5.1.106
Dietmar Schomburg, Ida Schomburg

18. maleamate amidohydrolase 3.5.1.107
Dietmar Schomburg, Ida Schomburg

19. UDP-3-O-acyl-N-acetylglucosamine deacetylase 3.5.1.108
Dietmar Schomburg, Ida Schomburg

20. streptothricin hydrolase 3.5.2.19
Dietmar Schomburg, Ida Schomburg

21. 5-nitroanthranilic acid aminohydrolase 3.5.99.8
Dietmar Schomburg, Ida Schomburg

22. Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase 3.6.1.53
Dietmar Schomburg, Ida Schomburg

23. UDP-2,3-diacylglucosamine diphosphatase 3.6.1.54
Dietmar Schomburg, Ida Schomburg

24. DNA helicase 3.6.4.12
Dietmar Schomburg, Ida Schomburg

25. RNA helicase 3.6.4.13
Dietmar Schomburg, Ida Schomburg

26. cyclohexane-1,2-dione hydrolase 3.7.1.11
Dietmar Schomburg, Ida Schomburg

27. cobalt-precorrin 5A hydrolase 3.7.1.12
Dietmar Schomburg, Ida Schomburg

28. 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase 3.7.1.13
Dietmar Schomburg, Ida Schomburg

29. malonyl-S-ACP decarboxylase 4.1.1.87
Dietmar Schomburg, Ida Schomburg

30. biotin-independent malonate decarboxylase 4.1.1.88
Dietmar Schomburg, Ida Schomburg

31. biotin-dependent malonate decarboxylase 4.1.1.89
Dietmar Schomburg, Ida Schomburg

32. peptidyl-glutamate 4-carboxylase 4.1.1.90
Dietmar Schomburg, Ida Schomburg

33. 3-hexulose-6-phosphate synthase 4.1.2.43
Dietmar Schomburg, Ida Schomburg

34. benzoyl-CoA-dihydrodiol lyase 4.1.2.44
Dietmar Schomburg, Ida Schomburg

35. trans-o-hydroxybenzylidenepyruvate hydratase-aldolase 4.1.2.45
Dietmar Schomburg, Ida Schomburg

36. aliphatic (R)-hydroxynitrile lyase 4.1.2.46
Dietmar Schomburg, Ida Schomburg

37. 3-hydroxy-d-aspartate aldolase 4.1.3.41
Dietmar Schomburg, Ida Schomburg

38. (6-4)DNA photolyase 4.1.99.13
Dietmar Schomburg, Ida Schomburg

39. spore photoproduct lyase 4.1.99.14
Dietmar Schomburg, Ida Schomburg

40. S-specific spore photoproduct lyase 4.1.99.15
Dietmar Schomburg, Ida Schomburg

41. methanogen homoaconitase 4.2.1.114
Dietmar Schomburg, Ida Schomburg

42. UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 4.2.1.115
Dietmar Schomburg, Ida Schomburg

43. 3-hydroxypropionyl-CoA dehydratase 4.2.1.116
Dietmar Schomburg, Ida Schomburg

44. 2-methylcitrate dehydratase (2-methyl-transaconitate forming)4.2.1.117
Dietmar Schomburg, Ida Schomburg

45. 3-dehydroshikimate dehydratase 4.2.1.118
Dietmar Schomburg, Ida Schomburg

46. enoyl-CoA hydratase 2 4.2.1.119
Dietmar Schomburg, Ida Schomburg

47. 4-hydroxybutanoyl-CoA dehydratase 4.2.1.120
Dietmar Schomburg, Ida Schomburg

48. colneleate synthase 4.2.1.121
Dietmar Schomburg, Ida Schomburg

49. ent-cassa-12,15-diene synthase 4.2.3.28
Dietmar Schomburg, Ida Schomburg

50. ent-sandaracopimaradiene synthase 4.2.3.29
Dietmar Schomburg, Ida Schomburg

51. ent-pimara-8(14),15-diene synthase 4.2.3.30
Dietmar Schomburg, Ida Schomburg

52. ent-pimara-9(11),15-diene synthase 4.2.3.31
Dietmar Schomburg, Ida Schomburg

53. levopimaradiene synthase 4.2.3.32
Dietmar Schomburg, Ida Schomburg

54. stemar-13-ene synthase 4.2.3.33
Dietmar Schomburg, Ida Schomburg

55. stemod-13(17)-ene synthase 4.2.3.34
Dietmar Schomburg, Ida Schomburg

56. syn-pimara-7,15-diene synthase 4.2.3.35
Dietmar Schomburg, Ida Schomburg

57. terpentetriene synthase 4.2.3.36
Dietmar Schomburg, Ida Schomburg

58. epi-isozizaene synthase 4.2.3.37
Dietmar Schomburg, Ida Schomburg

59.
α-bisabolene synthase 4.2.3.38
Dietmar Schomburg, Ida Schomburg

60. epi-cedrol synthase 4.2.3.39
Dietmar Schomburg, Ida Schomburg

61. (Z)-γ-bisabolene synthase 4.2.3.40
Dietmar Schomburg, Ida Schomburg

62. elisabethatriene synthase 4.2.3.41
Dietmar Schomburg, Ida Schomburg

63. aphidicolan-16β-ol synthase 4.2.3.42
Dietmar Schomburg, Ida Schomburg

64. fusicocca-2,10(14)-diene synthase 4.2.3.43
Dietmar Schomburg, Ida Schomburg

65. isopimara-7,15-diene synthase 4.2.3.44
Dietmar Schomburg, Ida Schomburg

66. phyllocladan-16α-ol synthase 4.2.3.45
Dietmar Schomburg, Ida Schomburg

67.
α-farnesene synthase 4.2.3.46
Dietmar Schomburg, Ida Schomburg

68.
β-farnesene synthase 4.2.3.47
Dietmar Schomburg, Ida Schomburg

69. (3S,6E)-nerolidol synthase 4.2.3.48
Dietmar Schomburg, Ida Schomburg

70. (3R,6E)-nerolidol synthase 4.2.3.49
Dietmar Schomburg, Ida Schomburg

71. 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 4.2.99.20
Dietmar Schomburg, Ida Schomburg

72. isochorismate lyase 4.2.99.21
Dietmar Schomburg, Ida Schomburg

73. chromopyrrolate synthase 4.3.1.26
Dietmar Schomburg, Ida Schomburg

74. threo-3-hydroxy-d-aspartate ammonia-lyase 4.3.1.27
Dietmar Schomburg, Ida Schomburg

75. carboxybiotin decarboxylase 4.3.99.2
Dietmar Schomburg, Ida Schomburg

76. heme ligase 4.99.1.8
Dietmar Schomburg, Ida Schomburg

77. hydantoin racemase 5.1.99.5
Dietmar Schomburg, Ida Schomburg

78. 6-phospho-3-hexuloisomerase 5.3.1.27
Dietmar Schomburg, Ida Schomburg

79. D-sedoheptulose 7-phosphate isomerase 5.3.1.28
Dietmar Schomburg, Ida Schomburg

80. syn-copalyl-diphosphate synthase 5.5.1.14
Dietmar Schomburg, Ida Schomburg

81. terpentedienyl-diphosphate synthase 5.5.1.15
Dietmar Schomburg, Ida Schomburg

82. halimadienyl-diphosphate synthase 5.5.1.16
Dietmar Schomburg, Ida Schomburg

83. 2-hydroxychromene-2-carboxylate isomerase 5.99.1.4
Dietmar Schomburg, Ida Schomburg

84. O-phospho-l-serine-tRNA ligase 6.1.1.27
Dietmar Schomburg, Ida Schomburg

85. ACP-SH:acetate ligase 6.2.1.35
Dietmar Schomburg, Ida Schomburg

86. 3-hydroxypropionyl-CoA synthase 6.2.1.36
Dietmar Schomburg, Ida Schomburg

87. L-cysteine:1d-myo-inositol 2-amino-2-deoxy-α-d-glucopyranoside ligase 6.3.1.13
Dietmar Schomburg, Ida Schomburg

88. diphthine-ammonia ligase 6.3.1.14
Dietmar Schomburg, Ida Schomburg

89. coenzyme F420-0:l-glutamate ligase 6.3.2.31
Dietmar Schomburg, Ida Schomburg

90. coenzyme γ-F420-2:α-l-glutamate ligase 6.3.2.32
Dietmar Schomburg, Ida Schomburg

91. tetrahydrosarcinapterin synthase 6.3.2.33
Dietmar Schomburg, Ida Schomburg

92. coenzyme F420-1:γ-l-glutamate ligase 6.3.2.34
Dietmar Schomburg, Ida Schomburg

93. D-alanine-d-serine ligase 6.3.2.35
Dietmar Schomburg, Ida Schomburg

94. 4-phosphopantoate-β-alanine ligase 6.3.2.36
Dietmar Schomburg, Ida Schomburg

Keywords: Life Sciences, Biochemistry, general, Molecular Medicine, Pharmacology/Toxicology, Food Science, Biotechnology, Veterinary Medicine