Tumor Angiogenesis

1. Tumor Angiogenesis: from Bench to Bedside
Judah Folkman

2. Vasculogenesis and Angiogenesis in Development
Anne Eichmann, Karine Bouvrée, Luc Pardanaud

3. Guidance of Vascular and Neuronal Network Formation
Carmen Ruiz Almodovar, Serena Zacchigna, Monica Autiero, Peter Carmeliet

4. The Angiogenic Switch in Tumorigenesis
Andreas Wicki, Gerhard Christofori

5. Pathophysiology and Clinical Implications of Vascular Endothelial Growth Factor
Napoleone Ferrara

6. Regulation of Angiogenesis and Vascular Homeostasis Through the Angiopoietin / Tie System
Hellmut G. Augustin, Ulrike Fiedler

7. Eph Receptors and Ephrins: Role in Vascular Development and Tumor Angiogenesis
Dana M. Brantley-Sieders, Jin Chen

8. The Role of the Neuropilins and Their Associated Plexin Receptors in Tumor Angiogenesis and Tumor Progression
Gera Neufeld, Ofra Kessler

9. Platelet-derived Growth Factor: Impact on Physiological and Tumor Angiogenesis
Arne Östman, Christer Betsholtz

10. Hypoxia and Tumour Angiogenesis
M. Christiane Brahimi-Horn, Julie Laferrière, Nathalie Mazure, Jacques Pouyssegur

11. Hypoxia and Angiogenesis in Glioblastomas
Till Acker, Karl H. Plate

12. Endogenous Inhibitors of Angiogenesis
Malin Sund, Raghu Kalluri

13. Thrombospondins and Angiogenesis
Nathan V. Lee, M. Luisa Iruela-Arispe

14. Molecular and Cellular Aspects of Heparanase
Neta Ilan, Liat Fux, Michael Elkin, Israel Vlodavsky

15. Vessel Maturation and Perivascular Cells
Anne M. Goodwin, PatriciaA. D’Amore

16. Adhesion Molecules in the Vascular Cell Cross-Talk
Ugo Cavallaro

17. Homing and Differentiation of Endothelial Progenitor Cells
Carmen Urbich, Emmanouil Chavakis, Stefanie Dimmeler

18. Molecular Players in Lymphangiogenesis
Marja Lohela, Kari Alitalo

19. The Relationship Between Tumors and the Lymphatics: Consequences for Metastasis
Jonathan P. Sleeman

20. Inflammation and Angiogenesis: Innate Immune Cells as Modulators of Tumor Vascularization
MargaretaM. Mueller

21. Arteriovenous Malformation in Mice and Men
Nicole Revencu, Laurence Boon, Miikka Vikkula

22. Vascular Endothelial Growth Factor Antibodies for Anti-Angiogenic Therapy
Hans-Peter Gerber, Megan E. Baldwin, Farbod Shojaei

23. Vascular Endothelial Growth Factor
Stephen R. Wedge, Juliane M. Jürgensmeier

24. Vascular Endothelial Growth Factor Receptor Antibodies for Anti-Angiogenic Therapy
Peter Bohlen, Zhenping Zhu, Daniel J. Hicklin

25. Angiopoietin-2 Antagonists for Anti-Angiogenic Therapy
Paul E. Hughes, Anthony Polverino, Jonathan D. Oliner, Richard L. Kendall

26. Anti-Angiogenic Therapy with Thrombospondins
Jack Lawler

27. The Use of Orthotopic Models to Validate Antivascular Therapies for Cancer
Robert R. Langley, Sun-Jin Kim, Isaiah J. Fidler

28. Vascular Tumor Targeting
Dragan Grabulovski, Dario Neri

29. Molecular Imaging of Targets and Therapeutics in Tumour Angiogenesis
James P. B. O’Connor, Daniela D. Rosa, Alan Jackson, Gordon C. Jayson

30. Imaging of Tumor Angiogenesis and Antiangiogenesis
Fabian Kiessling, Martin Krix

31. Visualization of Microcirculation and Anti-Angiogenic Tumor Therapy
Marcus Czabanka, Peter Vajkoczy

32. Cellular Actions of Angiogenesis Inhibitors on Blood Vessels
Peter Baluk, Beverly L. Falcón, Hiroya Hashizume, Barbara Sennino, Donald M. McDonald

33. Antiangiogenic Therapy for Normalization of Tumor Vasculature and Microenvironment
Rakesh K. Jain, Dan G. Duda

34. Metronomic Antiangiogenic Chemotherapy: Questions and Answers
Robert S. Kerbel, Urban Emmenegger, Shan Man, Raquel Munoz, Francesco Bertolini, Yuval Shared

35. The Development of Avastin
Robert Mass

36. Clinical Development of Sorafenib (BAY 43–9006) VEGFR and RAF Inhibitor
Dimitris Voliotis, J. Dumas

37. Clinical Development of the VEGFR Signalling Inhibitor AZD2171
Joachim Drevs, Clemens Unger

38. Clinical Development of Sunitinib Malate
Isan Chen, Carlo Bello, Zuleima Aguilar

39. The EGF(R) and VEGF(R) Pathways as Combined Targets for Anti-Angiogenesis Trials in Cancer Therapy
Klaas Hoekman, Hester Cruijsen, Giuseppe Giaccone

40. Imaging the Effect of Anti-Angiogenic Tumor Therapy in Clinical Studies
Bruno Morgan, Mark A. Horsfield

41. Vandetanib (ZACTIMA™; ZD6474): Preclinical and Clinical Development
Alan Barge, Anderson J. Ryan

42. Integrins: Targets for Anti-Angiogenic Therapy
Oliver Kisker

43. Thalidomide in Multiple Myeloma
Thomas M. Moehler, Jens Hillengass, Axel Glasmacher, Hartmut Goldschmidt

44. Surrogate Markers of Angiogenesis
Valentina Raia, Patrizia Mancuso, Francesco Bertolini

45. Vascular Disrupting Agents in Cancer Therapy
Gillian M. Tozer, Chryso Kanthou, David J. Chaplin

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Keywords: MEDICAL / Public Health MED078000