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| Table of contents I. Brain injury: ICP management and cerebral physiology 1. Cerebrovascular reactivity and autonomic drive following traumatic brain injury Andrea Lavinio, Bogdan Ene-Iordache, Ilaria Nodari, Alan Girardini, Elena Cagnazzi, Frank Rasulo, Piotr Smielewski, Marek Czosnyka, Nicola Latronico 2. A comparison between the transfer function of ABP to ICP and compensatory reserve index in TBI Sima Shahsavari, Tomas McKelvey, Thomas Skoglund, Catherine Eriksson Ritzèn 3. Cranioplasty effect on the cerebral hemodynamics and cardiac function Yoo-Dong Won, Do-Sung Yoo, Ki-Tae Kim, Suck-Gu Kang, Sang-Bock Lee, Dal-Soo Kim, Seong-Tai Hahn, Pil-Woo Huh, Kyung-Suck Cho, Chun-Kun Park 4. Hyperbaric oxygen therapy for consciousness disturbance following head injury in subacute phase Takehiro Nakamura, Yasuhiro Kuroda, Susumu Yamashita, Kenya Kawakita, Nobuyuki Kawai, Takashi Tamiya, Toshifumi Itano, Seigo Nagao 5. Gender-related differences in intracranial hypertension and outcome after traumatic brain injury Marek Czosnyka, Danila Radolovich, Marcella Balestreri, Andrea Lavinio, Peter Hutchinson, Ivan Timofeev, Peter Smielewski, John D. Pickard 6. Long term outcomes following decompressive craniectomy for severe head injury U. Meier, S. Ahmadi, T. Killeen, F. T. Al-Zain, J. Lemcke 7. Relationship of a cerebral autoregulatory index with outcome in head injured patients Martin Shaw, Ian Piper, Michael Daley 8. Assessment of cerebrovascular resistance with model of cerebrovascular pressure transmission Nithya Narayanan, Charles W. Leffler, Marek Czosnyka, Michael L. Daley 9. Generation of very low frequency cerebral blood flow fluctuations in humans Malgorzata Turalska, Miroslaw Latka, Marek Czosnyka, Krystyna Pierzchala, Bruce J. West 10. Accuracy of non-invasive ICP assessment can be increased by an initial individual calibration B. Schmidt, M. Weinhold, M. Czosnyka, S. A. May, R. Steinmeier, J. Klingelhöfer 11. The impact of ventricular catheter impregnated with antimicrobial agents on infections in patients with ventricular catheter: interim report George K. C. Wong, W. S. Poon, Stephanie C. C. P. Ng, Margaret Ip 12. Assessment of mitochondrial impairment and cerebral blood flow in severe brain injured patients Gunes A. Aygok, Anthony Marmarou, Panos P. Fatouros, Birgit Kettenmann, Ross M. Bullock 13. Mathematical models of cerebral hemodynamics for detection of vasospasm in major cerebral arteries Federico S. Cattivelli, Ali H. Sayed, Xiao Hu, Darrin Lee, Paul Vespa 14. Intracranial pressure in patients with sepsis D. Pfister, B. Schmidt, P. Smielewski, M. Siegemund, S. P. Strebel, S. Rüegg, S. C. U. Marsch, H. Pargger, L. A. Steiner 15. Intracranial pressure and cerebral oxygenation changes after decompressive craniectomy in children with severe traumatic brain injury A. A. Figaji, A. G. Fieggen, A. C. Argent, P. D. Roux, J. C. Peter 16. Are head injury guidelines changing the outcome of head injured children? A regional investigation P. A. Jones, I. R. Chambers, R. A. Minns, T. Y. M. Lo, L. M. Myles, A. J. W. Steers 17. Low frequency pressure waves of possible autonomic origin in severely head-injured children R. A. Minns, P. A. Jones, I. R. Chambers 18. Controlled lumbar drainage in medically refractory increased intracranial pressure. A safe and effective treatment Ali Murad, Samer Ghostine, Austin R. T. Colohan 19. Decompressive craniotomy: durotomy instead of duroplasty to reduce prolonged ICP elevation Ralf Burger, David Duncker, Naureen Uzma, Veit Rohde 20. Ventriculostomy for control of raised ICP in acute traumatic brain injury I. Timofeev, C. Dahyot-Fizelier, N. Keong, J. Nortje, P. G. Al-Rawi, M. Czosnyka, D. K. Menon, P. J. Kirkpatrick, A. K. Gupta, P. J. Hutchinson 21. Intracranial pressure variability and long-term outcome following traumatic brain injury Catherine J. Kirkness, Robert L. Burr, Pamela H. Mitchell 22. Predictive values of age and the Glasgow Coma Scale in traumatic brain injury patients treated with decompressive craniectomy Matthew B. Potts, John H. Chi, Michele Meeker, Martin C. Holland, J. Claude Hemphill III, Geoffrey T. Manley II. Hydrocephalus and cerebrospinal fluid dynamics 23. Noninvasive estimation of intracranial compliance in idiopathic NPH using MRI Mitsuhito Mase, Toshiaki Miyati, Harumasa Kasai, Koichiro Demura, Tomoshi Osawa, Masaki Hara, Yuta Shibamoto, Kazuo Yamada 24. The role of cerebrospinal fluid flow study using phase contrast MR imaging in diagnosing idiopathic normal pressure hydrocephalus F. T. Al-Zain, G. Rademacher, U. Meier, S. Mutze, J. Lemcke 25. Course of disease in patients with idiopathic normal pressure hydrocephalus (iNPH): a follow-up study 3, 4 and 5 years following shunt implantation U. Meier, J. Lemcke, F. Al-Zain 26. Chronic hydrocephalus that requires shunting in aneurysmal subarachnoid haemorrhage [a-SAH]: its impact on clinical outcome W. S. Poon, S. C. P. Ng, G. K. C. Wong, L. Y. C. Wong, M. T. V. Chan 27. Morphological changes of intracranial pressure pulses are correlated with acute dilatation of ventricles Xiao Hu, Peng Xu, Darrin J. Lee, Vespa Paul, Marvin Bergsneider 28. Pulse amplitude of intracranial pressure waveform in hydrocephalus Z. Czosnyka, N. Keong, D. J. Kim, D. Radolovich, P. Smielewski, A. Lavinio, E. A. Schmidt, S. Momjian, B. Owler, J. D. Pickard, M. Czosnyka 29. The influence of co-morbidity on the postoperative outcomes of patients with idiopathic normal pressure hydrocephalus (iNPH) U. Meier, J. Lemcke 30. ICM+, a flexible platform for investigations of cerebrospinal dynamics in clinical practice P. Smielewski, A. Lavinio, I. Timofeev, D. Radolovich, I. Perkes, J. D. Pickard, M. Czosnyka 31. Pathophysiology and diagnosis of spontaneous intracranial hypotension K. Shima, S. Ishihara, S. Tomura III. Advanced neuromonitoring 32. Intraoperative infrared brain surface blood flow monitoring during superficial temporal artery–middle cerebral artery anastomosis in a patient with moyamoya disease: clinical implication of the gradation value in postoperative clinical course – A case report Atsuhiro Nakagawa, Miki Fujimura, Tatsuhiko Arafune, Hideaki Suzuki, Ichiro Sakuma, Teiji Tominaga 33. Clinical study of craniospinal compliance non-invasive monitoring method A. Ragauskas, G. Daubaris, V. Petkus, R. Sliteris, R. Raisutis, I. Piper, S. Rocka, E. Jarzemskas, V. Matijosaitis 34. Cerebral CO C. Puppo, G. Fariña, L. López Franco, E. Caragna, A. Biestro 35. Acetazolamide vasoreactivity evaluated by transcranial power harmonic imaging and Doppler sonography T. Shiogai, K. Ikeda, A. Morisaka, Y. Nagakane, T. Mizuno, M. Nakagawa, H. Furuhata 36. A new semi-invasive method for two dimensional pO Jan Warnat, Gregor Liebsch, Eva-Maria Stoerr, Alexander Brawanski, Chris Woertgen 37. The relationship between intracranial pressure and brain oxygenation following traumatic brain injury in sheep Robert Vink, Kartik D. Bahtia, Peter L. Reilly 38. Dual microdialysis probe monitoring for patients with traumatic brain injury Hiroyasu Koizumi, Hirosuke Fujisawa, Sadahiro Nomura, Shoichi Kato, Koji Kajiwara, Masami Fujii, Michiyasu Suzuki 39. In vitro comparison of two generations of Licox and Neurotrend catheters Iain Haitsma, Guy Rosenthal, Diane Morabito, Mark Rollins, Andrew I. R. Maas, Geoffrey T. Manley 40. Cerebral metabolism monitoring during hypothermia following resuscitation from cardiopulmonary arrest Takehiro Nakamura, Yasuhiro Kuroda, Natsuyo Torigoe, Yuko Abe, Susumu Yamashita, Kenya Kawakita, Nobuyuki Kawai, Takashi Tamiya, Toshifumi Itano, Seigo Nagao 41. Nitric oxide in acute brain injury: a pilot study of NO Keri L. H. Carpenter, Ivan Timofeev, Pippa G. Al-Rawi, David K. Menon, John D. Pickard, Peter J. Hutchinson IV. Biomedical informatics 42. The brain monitoring with Information Technology (BrainIT) collaborative network: data validation results Martin Shaw, Ian Piper, Iain Chambers, Giuseppe Citerio, Per Enblad, Barbara Gregson, Tim Howells, Karl Kiening, Julia Mattern, Pelle Nilsson, Arminas Ragauskas, Juan Sahuquillo, YH Yau 43. BrainIT collaborative network: analyses from a high time-resolution dataset of head injured patients Iain Chambers, Barbara Gregson, Giuseppe Citerio, Per Enblad, Tim Howells, Karl Kiening, Julia Mattern, Pelle Nilsson, Ian Piper, Arminas Ragauskas, Juan Sahuquillo, Y. H. Yau 44. Pilot application of fractal characterisation and its response to change on physiological wave forms Martin Shaw, Ian Piper V. Neuroimaging 45. The predictive value of ICP as compared to magnetic resonance imaging in comatose patients after head injury R. Firsching, F.-W. Roehl, D.-H. Woischneck, N. John, M. Skalej 46. Metabolic disturbance without brain ischemia in traumatic brain injury: A positron emission tomography study Nobuyuki Kawai, Takehiro Nakamura, Takashi Tamiya, Seigo Nagao 47. Concordant biology underlies discordant imaging findings: diffusivity behaves differently in grey and white matter post acute neurotrauma Virginia F. J. Newcombe, Guy B. Williams, Jurgens Nortje, Peter G. Bradley, Doris A. Chatfield, Joanne G. Outtrim, Sally G. Harding, Jonathan P. Coles, Bala Maiya, Jonathan H. Gillard, Peter J. Hutchinson, John D. Pickard, T. Adrian Carpenter, David K. Menon 48. Qualitative aspects of cranial CT perfusion scanning in a mixed neurosurgical patient collective S. Wolf, N. Kuckertz, M. Bauer, L. Schürer, C. Lumenta 49. Study of perfusion in and around cerebral contusions by means of computed tomography Bart Depreitere, Richard Aviv, Sean Symons, Michael Schwartz, Walter Coudyzer, Guy Wilms, Guy Marchal 50. Magnetic resonance measurement of blood and CSF flow rates with phase contrast – normal values, repeatability and CO Stefan K. Piechnik, Paul E. Summers, Peter Jezzard, James V. Byrne VI. ICP: Brain complicance, biophysics, and biomechanics 51. Motor trephine syndrome: A mechanistic hypothesis Shirley I. Stiver, Max Wintermark, Geoffrey T. Manley 52. Biomechanical modeling of decompressive craniectomy in traumatic brain injury Chun Ping Gao, Beng Ti Ang 53. Coupling of sagittal sinus pressure and cerebrospinal fluid pressure in idiopathic intracranial hypertension – a preliminary report J. D. Pickard, Z. Czosnyka, M. Czosnyka, B. Owler, J. N. Higgins 54. The measurement of brain tissue stiffness in-vivo I. R. Chambers, D. Martin, A. Clark, A. Nicklin, A. D. Mendelow, P. Mitchell VII. Stroke, subarachnoid hemorrhage, and intracerebral hematoma 55. Changes in brain biochemistry and oxygenation in the zone surrounding primary intracerebral hemorrhage Ernest Wang, Chi Long Ho, Kah Keow Lee, Ivan Ng, Beng Ti Ang 56. Prediction of early mortality in primary intracerebral hemorrhage in an asian population Beng Ti Ang, Siew Pang Chan, Kah Keow Lee, Ivan Ng 57. Ischemic events after carotid interventions in relationship to baseline cerebrovascular reactivity George K. -C. Wong, Stephanie C. -P. Ng, Matthew T. -V. Chan, David T. -F. Sun, Winnie W. -M. Lam, Joseph M. -K. Lam, Wai S. Poon 58. Effect of increased intracranial pressure on cerebral vasospasm in SAH Krissanee Karnchanapandh 59. Cerebral blood flow thresholds predicting new hypoattenuation areas due to macrovascular ischemia during the acute phase of severe and complicated aneurysmal subarachnoid hemorrhage. A preliminary study A. Chieregato, A. Tanfani, A. Noto, S. Fronza, F. Cocciolo, E. Fainardi 60. Hyperbaric oxygen preconditioning activates ribosomal protein S6 kinases and reduces brain swelling after intracerebral hemorrhage Z. Qin, Y. Hua, W. Liu, R. Silbergleit, Y. He, R. F. Keep, J. T. Hoff, G. Xi 61. Stroke with subarachnoid hemorrhage: assessment of cerebrovascular pressure regulation and simulated cerebrovascular resistance Michael L. Daley, Nithya Narayanan, Charles W. Leffler, Per Kristian Eide 62. Effects of melatonin in early brain injury following subarachnoid hemorrhage Robert E. Ayer, Takashi Sugawara, John H. Zhang 63. Decompressive craniectomy for hemispheric infarction: predictive factors for six month rehabilitation outcome G. K. Wong, J. Kung, S. C. Ng, X. L. Zhu, W. S. Poon 64. Effects of temperature changes on cerebral biochemistry in spontaneous intracerebral hematoma Ernest Wang, Chi Long Ho, Kah Keow Lee, Ivan Ng, Beng Ti Ang 65. Increased levels of CSF heart-type fatty acid-binding protein and tau protein after aneurysmal subarachnoid hemorrhage E. R. Zanier, L. Longhi, M. Fiorini, L. Cracco, A. Bersano, T. Zoerle, V. Branca, S. Monaco, N. Stocchetti VIII. Experimental studies and models 66. DNA vaccination against neurite growth inhibitors to enhance functional recovery following traumatic brain injury Yi Zhang, Beng Ti Ang, Zhi Cheng Xiao, Ivan Ng 67. Ischemic blood-brain barrier and amyloid in white matter as etiological factors in leukoaraiosis Ryszard Pluta, Slawomir Januszewski, Marzena Ulamek 68. Matrix metalloproteinase inhibition attenuates brain edema after surgical brain injury Vikram Jadhav, Mitsuo Yamaguchi, Andre Obenaus, John H. Zhang 69. Thrombin enhances glioma growth Ya Hua, Lingling Tang, Richard F. Keep, Julian T. Hoff, Jason Heth, Guohua Xi, Karin M. Muraszko 70. The antioxidant effects of melatonin in surgical brain injury in rats Steve Lee, Vikram Jadhav, Robert Ayer, Hugo Rojas, Amy Hyong, Tim Lekic, Gary Stier, Robert Martin, John H. Zhang 71. Dymanics of matrix-metalloproteinase 9 after brain trauma – results of a pilot study Martin Kolar, Jan Pachl, Helena Tomasova, Pavel Haninec 72. Experimental subarachnoid hemorrhage in the rat: influences of nimodipine Sebastian Thomas, Birte Herrmann, Madjid Samii, Thomas Brinker 73. Neuroprotective effect of C1-inhibitor following traumatic brain injury in mice L. Longhi, C. Perego, E. R. Zanier, F. Ortolano, P. Bianchi, N. Stocchetti, M. G. Simoni 74. Up-regulation of L type amino acid transporter 1 after spinal cord injury in rats Terushige Toyooka, Hiroshi Nawashiro, Nariyoshi Shinomiya, Akiko Yano, Hidetoshi Ooigawa, Atsushi Ohsumi, Yoichi Uozumi, Youichi Yanagawa, Hirotaka Matsuo, Katsuji Shima 75. Cortical expression of prolactin (PRL), growth hormone (GH) and adrenocorticotrophic hormone (ACTH) is not increased in experimental traumatic brain injury J. C. Goodman, L. Cherian, C. S. Robertson 76. Simvastatin attenuates cerebral vasospasm and improves outcomes by upregulation of PI3K/Akt pathway in a rat model of subarachnoid hemorrhage Takashi Sugawara, Vikram Jadhav, Robert Ayer, John Zhang 77. HIF-1 alpha inhibition ameliorates neonatal brain damage after hypoxic-ischemic injury Wanqiu Chen, Vikram Jadhav, Jiping Tang, John H. Zhang 78. Simvastatin treatment in surgically induced brain injury in rats Steve Lee, Vikram Jadhav, Tim Lekic, Amy Hyong, Martin Allard, Gary Stier, Robert Martin, John Zhang 79. 3% Hypertonic saline following subarachnoid hemorrhage in rats Steve Lee, Gary Stier, Suzzanne Marcantonio, Tim Lekic, Martin Allard, Robert Martin, John Zhang 80. Effect of traumatic brain injury on cognitive function in mice lacking p55 and p75 tumor necrosis factor receptors L. Longhi, F. Ortolano, E. R. Zanier, C. Perego, N. Stocchetti, M. G. Simoni 81. Brain contusions induce a strong local overexpression of MMP-9. Results of a pilot study A. Vilalta, J. Sahuquillo, M. A. Poca, J. Rios, E. Cuadrado, A. Ortega-Aznar, M. Riveiro, J. Montaner 82. Shock wave-induced brain injury in rat: Novel traumatic brain injury animal model Atsuhiro Nakagawa, Miki Fujimura, Kaoruko Kato, Hironobu Okuyama, Tokitada Hashimoto, Kazuyoshi Takayama, Teiji Tominaga 83. Modulation of AQP4 expression by the selective V1a receptor antagonist, SR49059, decreases trauma-induced brain edema Keisuke Taya, Salih Gulsen, Kenji Okuno, Ruth Prieto, Christina R. Marmarou, Anthony Marmarou 84. The modulation of aquaporin-4 by using PKC-activator (phorbol myristate acetate) and V1a receptor antagonist (SR49059) following middle cerebral artery occlusion/reperfusion in the rat Kenji Okuno, Keisuke Taya, Christina R. Marmarou, Pinar Ozisik, Giovanna Fazzina, Andrea Kleindienst, Salih Gulsen, Anthony Marmarou 85. Pro-inflammatory and pro-apoptotic elements of the neuroinflammatory response are activated in traumatic brain injury J. C. Goodman, M. Van, S. P. Gopinath, C. S. Robertson 86. Protective effect of hyperbaric oxygen therapy on experimental brain contusions Cornelia Voigt, Annette Förschler, Matthias Jaeger, Jürgen Meixensberger, Lea Küppers-Tiedt, Martin U. Schuhmann | ||||||||||||||||||||||||
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