Nuclear Reprogramming and Stem Cells

1. Introduction
John Gurdon, Azim Surani

2. Introduction: Stem Cells – What Next?
Ian Wilmut

3. Inherent Nuclear Reprogramming in Mammalian Embryos
Ai Khim Lim, Barbara B. Knowles, Toshie Kai, Daniel M. Messerschmidt

4. Epigenetic Reprogramming During Somatic Cell Nuclear Transfer and the Development of Primordial Germ Cells
Lyle Armstrong, Majlinda Lako

5. Epigenetic Reprogramming with Oocyte Molecules
Ramiro Alberio, Andrew D. Johnson

6. Cell Fusion-Mediated Nuclear Reprogramming of Somatic Cells
Kunio Hirano, Takashi Tada

7. Generation of Induced Pluripotent Stem Cells from Somatic Cells
Masato Nakagawa

8. The Consequences of Reprogramming a Somatic Cell for Mitochondrial DNA Transmission, Inheritance and Replication
Justin C. St. John, Keith H. S. Campbell

9. The Function of Nanog in Pluripotency
Nicholas Mullin, Ian Chambers

10. Function of Oct3/4 and Sox2 in Pluripotency
Shinji Masui

11. Generation of Neural Cells from Pluripotent Stem Cells
Takuya Shimazaki, Hideyuki Okano

12. Noncell Autonomous Reprogramming to a Pluripotent State
Sowmya Parameswaran, Sudha Balasubramanian, Iqbal Ahmad

13. Toward Regeneration of Retinal Function Using Pluripotent Stem Cells
Fumitaka Osakada, Masayo Takahashi

14. Reprogramming Towards Pancreatic β-Cells
Kevin Docherty

15. Pancreatic Plasticity and Reprogramming: Novel Directions Towards Disease Therapy
Spencer Willet, Chris Wright

16. Phenotype and Developmental Potential of Cardiomyocytes from Induced Pluripotent Stem Cells and Human Embryonic Stem Cells
Christopher Rao, Nadire N. Ali, Thanos Athanasiou, Cesare Terracciano, Sian Harding

17. The Generation of Disease-Specific Cell Lines and Their Use for Developing Drug Therapies
Stefanie Gögel, Stephen L. Minger

18. Advances in the Culture of Human Embryonic Stem Cells
Takamichi Miyazaki, Hirofumi Suemori

19. Culture Adaptation of Pluripotent Stem Cells: Challenges and Opportunities
Neil J. Harrison, Duncan Baker, Peter W. Andrews

20. Epilogue
Takashi Tada, Justin Ainscough, Shinya Yamanaka

Keywords: Life Sciences, Stem Cells, Cell Biology, Biotechnology