Ritsner, Michael S.

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes


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Table of contents

I. Methodological and Technological Advances

1. Where Do We Stand in the Quest for Neuropsychiatric Biomarkers and Endophenotypes and What Next?
Michael S. Ritsner, Irving I. Gottesman

2. Methodological and Statistical Issues in the Use of Biomarkers in Clinical and Research Studies
Ryan J. Lieshout, Peter Szatmari

3. Challenging the Genetic Complexity of Schizophrenia by Use of Intermediate Phenotypes
Assen Jablensky

4. Translational Medicine: Functional Biomarkers for Drug Development of “Cognitive Enhancers” in Schizophrenia
Georg Winterer

5. Leveraging High-Dimensional Neuroimaging Data in Genetic Studies of Neuropsychiatric Disease
Cinnamon S. Bloss, Trygve E. Bakken, Alexander H. Joyner, Nicholas J. Schork

6. Proteomics as a New Tool for Biomarker-Discovery in Neuropsychiatric Disorders
Thomas J. Raedler, Harald Mischak, Holger Jahn, Klaus Wiedemann

7. Schizophrenia Endophenotypes as Treatment Targets
Stephen I. Deutsch, Barbara L. Schwartz, Richard B. Rosse, John Mastropaolo, Ayman H. Fanous, Abraham Weizman, Jessica A. Burket, Brooke L. Gaskins

II. Neuropsychological, Neurocognitive and Neurophysiological Domains

8. Neuropsychological Endophenotypes in Schizophrenia and Bipolar I Disorder: Yields from the Finnish Family and Twin Studies
Annamari Tuulio-Henriksson, Jonna Perälä, Irving I. Gottesman, Jaana Suvisaari

9. Is More Cognitive Experimental Psychopathology of Schizophrenia Really Necessary? Challenges and Opportunities
Angus W. MacDonald

10. Intellectual Functioning as an Endophenotype for Schizophrenia
Odette Wilde

11. Emotion Recognition Deficits as a Neurocognitive Marker of Schizophrenia Liability
Renata Schoeman, Dana J. H. Niehaus, Liezl Koen, Jukka M. Leppänen

12. The Use of Neurocognitive Endophenotypes in Large-Scale Family Genetic Studies of Schizophrenia
William P. Horan, Tiffany A. Greenwood, David L. Braff, Raquel E. Gur, Michael F. Green

13. Neurocognitive Endophenotypes for Bipolar Disorder: Evidence from Case-Control, Family and Twin Studies
Eugenia Kravariti, Fergus Kane, Robin M. Murray

14. Trait and State Markers of Schizophrenia in Visual Processing
Yue Chen, Daniel Norton, Ryan McBain

15. Visual Scanning Abnormalities as Biomarker for Schizophrenia
Patricia E. G. Bestelmeyer

16. Biomarkers and Endophenotypes in Eating Disorders
Carolina Lopez, Marion Roberts, Janet Treasure

17. Movement Abnormalities: A Putative Biomarker of Risk for Psychosis
Vijay A. Mittal, Elaine F. Walker

Keywords: Biomedicine, Neurosciences, Psychiatry, Neurology, Human Genetics, Biomedicine general

Publication year
Page amount
287 pages
Medicine, Health Care, Mode

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